Idiopathic intracranial hypertension

References

Key articles

Wall M. Idiopathic intracranial hypertension. Neurol Clin. 2010 Aug;28(3):593-617.Full text  Abstract

Johnson LN, Krohel GB, Madsen RW, et al. The role of weight loss and acetazolamide in the treatment of idiopathic intracranial hypertension (pseudotumor cerebri). Ophthalmology. 1998 Dec;105(12):2313-7. Abstract

Hayreh SS. Pathogenesis of oedema of the optic disc (papilloedema): a preliminary report. Br J Ophthalmol. 1964 Oct;48:522-43.Full text  Abstract

Smith JL. Whence pseudotumor cerebri? J Clin Neuroophthalmol. 1985 Mar;5(1):55-6. Abstract

Frisen L. Swelling of the optic nerve head: a staging scheme. J Neurol Neurosurg Psychiatry. 1982 Jan;45(1):13-8.Full text  Abstract

NORDIC Idiopathic Intracranial Hypertension Study Group Writing Committee; Wall M, McDermott MP, Kieburtz KD, et al. Effect of acetazolamide on visual function in patients with idiopathic intracranial hypertension and mild visual loss: the idiopathic intracranial hypertension treatment trial. JAMA. 2014 Apr 23-30;311(16):1641-51.Full text  Abstract

Hoffmann J, Mollan SP, Paemeleire K, et al. European Headache Federation guideline on idiopathic intracranial hypertension. J Headache Pain. 2018 Oct 8;19(1):93.Full text  Abstract

Sinclair AJ, Burdon MA, Nightingale PG, et al. Low energy diet and intracranial pressure in women with idiopathic intracranial hypertension: prospective cohort study. BMJ. 2010 Jul 7;341:c2701.Full text  Abstract

Reference articles

1. Wall M. Idiopathic intracranial hypertension. Neurol Clin. 2010 Aug;28(3):593-617.Full text  Abstract

2. Shah VA, Kardon RH, Lee AG, et al. Long-term follow-up of idiopathic intracranial hypertension: the Iowa experience. Neurology. 2008 Feb 19;70(8):634-40. Abstract

3. Ghaffari-Rafi A, Mehdizadeh R, Ko AWK, et al. Idiopathic intracranial hypertension in the United States: demographic and socioeconomic disparities. Front Neurol. 2020 Sep 8;11:869.Full text  Abstract

4. Mollan SP, Aguiar M, Evison F, et al. The expanding burden of idiopathic intracranial hypertension. Eye (Lond). 2019 Mar;33(3):478-85.Full text  Abstract

5. Radhakrishnan K, Thacker AK, Bohlaga NH, et al. Epidemiology of idiopathic intracranial hypertension: a prospective and case-control study. J Neurol Sci. 1993 May;116(1):18-28. Abstract

6. Durcan FJ, Corbett JJ, Wall M. The incidence of pseudotumor cerebri: population studies in Iowa and Louisiana. Arch Neurol. 1988 Aug;45(8):875-7. Abstract

7. Miah L, Strafford H, Fonferko-Shadrach B, et al. Incidence, prevalence and healthcare outcomes in idiopathic intracranial hypertension: a population study. Neurology. 2021 Jan 20;96(8):e1251-61.Full text  Abstract

8. Balcer LJ, Liu GT, Forman S, et al. Idiopathic intracranial hypertension: relation of age and obesity in children. Neurology. 1999 Mar 10;52(4):870-2. Abstract

9. Sundholm A, Burkill S, Waldenlind E, et al. A national Swedish case-control study investigating incidence and factors associated with idiopathic intracranial hypertension. Cephalalgia. 2021 Dec;41(14):1427-36.Full text  Abstract

10. Radhakrishnan K, Ahlskog JE, Cross SA, et al. Idiopathic intracranial hypertension (pseudotumor cerebri): descriptive epidemiology in Rochester, Minn, 1976 to 1990. Arch Neurol. 1993 Jan;50(1):78-80. Abstract

11. Johnson LN, Krohel GB, Madsen RW, et al. The role of weight loss and acetazolamide in the treatment of idiopathic intracranial hypertension (pseudotumor cerebri). Ophthalmology. 1998 Dec;105(12):2313-7. Abstract

12. Joynt RJ, Sahs AL. Brain swelling of unknown cause. Neurology. 1956 Nov;6(11):801-3. Abstract

13. Wall M, Dollar JD, Sadun AA, et al. Idiopathic intracranial hypertension: lack of histologic evidence for cerebral edema. Arch Neurol. 1995 Feb;52(2):141-5. Abstract

14. Hayreh SS. Pathogenesis of oedema of the optic disc (papilloedema): a preliminary report. Br J Ophthalmol. 1964 Oct;48:522-43.Full text  Abstract

15. Wall M, White WN 2nd. Asymmetric papilledema in idiopathic intracranial hypertension: prospective interocular comparison of sensory visual function. Invest Ophthalmol Vis Sci. 1998 Jan;39(1):134-42.Full text  Abstract

16. Ko MW, Chang SC, Ridha MA, et al. Weight gain and recurrence in idiopathic intracranial hypertension: a case-control study. Neurology. 2011 May 3;76(18):1564-7. Abstract

17. Deonna T, Guignard JP. Acute intracranial hypertension after nalidixic acid administration. Arch Dis Child. 1974 Sep;49(9):743.Full text  Abstract

18. Mushet GR. Pseudotumor and nitrofurantoin therapy. Arch Neurol. 1977 Apr;34(4):257. Abstract

19. Konomi H, Imai M, Nihei K, et al. Indomethacin causing pseudotumor cerebri in Bartter's syndrome. N Engl J Med. 1978 Apr 13;298(15):855. Abstract

20. Larizza D, Colombo A, Lorini R, et al. Ketoprofen causing pseudotumor cerebri in Bartter's syndrome. N Engl J Med. 1979 Apr 5;300(14):796. Abstract

21. Feldman MH, Schlezinger NS. Benign intracranial hypertension associated with hypervitaminosis A. Arch Neurol. 1970 Jan;22(1):1-7. Abstract

22. Spector RH, Carlisle J. Pseudotumor cerebri caused by a synthetic vitamin A preparation. Neurology. 1984 Nov;34(11):1509-11. Abstract

23. Colucciello M. Pseudotumor cerebri induced by all-trans retinoic acid treatment of acute promyelocytic leukemia. Arch Ophthalmol. 2003 Jul;121(7):1064-5. Abstract

24. Van Dop C, Conte FA, Koch TK, et al. Pseudotumor cerebri associated with initiation of levothyroxine therapy for juvenile hypothyroidism. N Engl J Med. 1983 May 5;308(18):1076-80. Abstract

25. Saul RF, Hamburger HA, Selhorst JB. Pseudotumor cerebri secondary to lithium carbonate. JAMA. 1985 May 17;253(19):2869-70. Abstract

26. Shah A, Roberts T, McQueen IN, et al. Danazol and benign intracranial hypertension. Br Med J. 1987 May 23;294(6583):1323.Full text  Abstract

27. Chiu AM, Chuenkongkaew WL, Cornblath WT, et al. Minocycline treatment and pseudotumor cerebri syndrome. Am J Ophthalmol. 1998 Jul;126(1):116-21. Abstract

28. Gardner K, Cox T, Digre KB. Idiopathic intracranial hypertension associated with tetracycline use in fraternal twins: case reports and review. Neurology. 1995 Jan;45(1):6-10. Abstract

29. Orme DR, Vegunta S, Miller MA, et al. A comparison between the clinical features of pseudotumor cerebri secondary to tetracyclines and idiopathic intracranial hypertension. Am J Ophthalmol. 2020 Dec;220:177-82. Abstract

30. Thurtell MJ, Trotti LM, Bixler EO, et al. Obstructive sleep apnea in idiopathic intracranial hypertension: comparison with matched population data. J Neurol. 2013 Jul;260(7):1748-51.Full text  Abstract

31. NORDIC Idiopathic Intracranial Hypertension Study Group; Wall M, Kupersmith MJ, Kieburtz KD, et al. The idiopathic intracranial hypertension treatment trial: clinical profile at baseline. JAMA Neurol. 2014 Jun;71(6):693-701.Full text  Abstract

32. Klein A, Dotan G, Kesler A. Familial occurrence of idiopathic intracranial hypertension. Isr Med Assoc J. 2018 Sep;20(9):557-60.Full text  Abstract

33. Kuehn MH, Mishra R, Deonovic BE, et al. Genetic survey of adult-onset idiopathic intracranial hypertension. J Neuroophthalmol. 2019 Mar;39(1):50-5.Full text  Abstract

34. Blanch RJ, Vasseneix C, Liczkowski A, et al. Differing presenting features of idiopathic intracranial hypertension in the UK and US. Eye (Lond). 2019 Jun;33(6):1014-9.Full text  Abstract

35. Keltner JL, Johnson CA, Cello KE, et al. Baseline visual field findings in the Idiopathic Intracranial Hypertension Treatment Trial (IIHTT). Invest Ophthalmol Vis Sci. 2014 Apr 29;55(5):3200-7.Full text  Abstract

36. Smith JL. Whence pseudotumor cerebri? J Clin Neuroophthalmol. 1985 Mar;5(1):55-6. Abstract

37. Frisen L. Swelling of the optic nerve head: a staging scheme. J Neurol Neurosurg Psychiatry. 1982 Jan;45(1):13-8.Full text  Abstract

38. Wall M, George D. Idiopathic intracranial hypertension: a prospective study of 50 patients. Brain. 1991 Feb;114 (pt 1A):155-80. Abstract

39. Friedman DI, Quiros PA, Subramanian PS, et al. Headache in idiopathic intracranial hypertension: Findings from the Idiopathic Intracranial Hypertension Treatment Trial. Headache. 2017 Sep;57(8):1195-205. Abstract

40. Wall M. The headache profile of idiopathic intracranial hypertension. Cephalalgia. 1990 Dec;10(6):331-5. Abstract

41. Sadun AA, Currie JN, Lessell S. Transient visual obscurations with elevated optic discs. Ann Neurol. 1984 Oct;16(4):489-94. Abstract

42. Wall M, Falardeau J, Fletcher WA, et al. Risk factors for poor visual outcome in patients with idiopathic intracranial hypertension. Neurology. 2015 Sep 1;85(9):799-805. Abstract

43. Meador KJ, Swift TR. Tinnitus from intracranial hypertension. Neurology. 1984 Sep;34(9):1258-61. Abstract

44. Scott CJ, Kardon RH, Lee AG, et al. Diagnosis and grading of papilledema in patients with raised intracranial pressure using optical coherence tomography vs clinical expert assessment using a clinical staging scale. Arch Ophthalmol. 2010 Jun;128(6):705-11. Abstract

45. Wall M, Thurtell MJ; NORDIC Idiopathic Intracranial Hypertension Study Group. Optic disc haemorrhages at baseline as a risk factor for poor outcome in the Idiopathic Intracranial Hypertension Treatment Trial. Br J Ophthalmol. 2017 Sep;101(9):1256-60. Abstract

46. Mollan SP, Davies B, Silver NC, et al. Idiopathic intracranial hypertension: consensus guidelines on management. J Neurol Neurosurg Psychiatry. 2018 Oct;89(10):1088-100.Full text  Abstract

47. Neville L, Egan RA. Frequency and amplitude of elevation of cerebrospinal fluid resting pressure by the Valsalva maneuver. Can J Ophthalmol. 2005 Dec;40(6):775-7. Abstract

48. Lim MJ, Lin JP. The effects of carbon dioxide on measuring cerebral spinal fluid pressure. Childs Nerv Syst. 2009 Jul;25(7):783-4. Abstract

49. Bono F, Quattrone A. CSF opening pressure: reference interval and the effect of body mass index. Neurology. 2007 Apr 24;68(17):1439-40. Abstract

50. Corbett JJ, Mehta MP. Cerebrospinal fluid pressure in normal obese subjects and patients with pseudotumor cerebri. Neurology. 1983 Oct;33(10):1386-8. Abstract

51. Whiteley W, Al-Shahi R, Warlow CP, et al. CSF opening pressure: reference interval and the effect of body mass index. Neurology. 2006 Nov 14;67(9):1690-1. Abstract

52. Berdahl JP, Fleischman D, Zaydlarova J, et al. Body mass index has a linear relationship with cerebrospinal fluid pressure. Invest Ophthalmol Vis Sci. 2012 Mar 15;53(3):1422-7.Full text  Abstract

53. Avery RA, Shah SS, Licht DJ, et al. Reference range for cerebrospinal fluid opening pressure in children. N Engl J Med. 2010 Aug 26;363(9):891-3.Full text  Abstract

54. NORDIC Idiopathic Intracranial Hypertension Study Group Writing Committee; Wall M, McDermott MP, Kieburtz KD, et al. Effect of acetazolamide on visual function in patients with idiopathic intracranial hypertension and mild visual loss: the idiopathic intracranial hypertension treatment trial. JAMA. 2014 Apr 23-30;311(16):1641-51.Full text  Abstract

55. Hoffmann J, Mollan SP, Paemeleire K, et al. European Headache Federation guideline on idiopathic intracranial hypertension. J Headache Pain. 2018 Oct 8;19(1):93.Full text  Abstract

56. Newborg B. Pseudotumor cerebri treated by rice reduction diet. Arch Intern Med. 1974 May;133(5):802-7. Abstract

57. Sinclair AJ, Burdon MA, Nightingale PG, et al. Low energy diet and intracranial pressure in women with idiopathic intracranial hypertension: prospective cohort study. BMJ. 2010 Jul 7;341:c2701.Full text  Abstract

58. Amaral JF, Tsiaris W, Morgan T, et al. Reversal of benign intracranial hypertension by surgically induced weight loss. Arch Surg. 1987 Aug;122(8):946-9. Abstract

59. Sugerman HJ, Felton WL 3rd, Sismanis A, et al. Gastric surgery for pseudotumor cerebri associated with severe obesity. Ann Surg. 1999 May;229(5):634-40.Full text  Abstract

60. Fridley J, Foroozan R, Sherman V, et al. Bariatric surgery for the treatment of idiopathic intracranial hypertension. J Neurosurg. 2011 Jan;114(1):34-9. Abstract

61. Friedman DI, Streeten DH. Idiopathic intracranial hypertension and orthostatic edema may share a common pathogenesis. Neurology. 1998 Apr;50(4):1099-104. Abstract

62. Rubin RC, Henderson ES, Ommaya AK, et al. The production of cerebrospinal fluid in man and its modification by acetazolamide. J Neurosurg. 1966 Oct;25(4):430-6. Abstract

63. Smith SV, Friedman DI. The idiopathic intracranial hypertension treatment trial: a review of the outcomes. Headache. 2017 Sep;57(8):1303-10. Abstract

64. Piper RJ, Kalyvas AV, Young AM, et al. Interventions for idiopathic intracranial hypertension. Cochrane Database Syst Rev. 2015 Aug 7;(8):CD003434.Full text  Abstract

65. Lubow M, Kuhr L. Pseudotumor cerebri: comments on practical management. In: Glaser JS, Smith JL, eds. Neuro-ophthalmology, Vol. IX. St Louis, MO: CV Mosby; 1976:199-206.

66. Tomsak RL, Niffenegger AS, Remler BF. Treatment of pseudotumor cerebri with Diamox (acetazolamide). J Clin Neuroophthalmol. 1988;8:93-8.

67. Lichter PR. Reducing side effects of carbonic anhydrase inhibitors. Ophthalmology. 1981 Mar;88(3):266-9. Abstract

68. Garner LL, Carl EF, Ferwerda JR. Advantages of sustained-release therapy with acetazolamide in glaucoma. Am J Ophthalmol. 1963;55:323-7.

69. Zimran A, Beutler E. Can the risk of acetazolamide-induced aplastic anemia be decreased by periodic monitoring of blood cell counts? Am J Ophthalmol. 1987 Dec 15;104(6):654-8. Abstract

70. ten Hove MW, Friedman DI, Patel AD, Irrcher I, et al; NORDIC Idiopathic Intracranial Hypertension Study Group. Safety and tolerability of acetazolamide in the Idiopathic Intracranial Hypertension Treatment Trial. J Neuroophthalmol. 2016 Mar;36(1):13-9. Abstract

71. Corbett JJ. The 1982 Silversides lecture: problems in the diagnosis and treatment of pseudotumor cerebri. Can J Neurol Sci. 1983 Nov;10(4):221-9. Abstract

72. Pollay M, Fullenwider C, Roberts PA, et al. Effect of mannitol and furosemide on blood-brain osmotic gradient and intracranial pressure. J Neurosurg. 1983 Dec;59(6):945-50. Abstract

73. Roberts PA, Pollay M, Engles C, et al. Effect on intracranial pressure of furosemide combined with varying doses and administration rates of mannitol. J Neurosurg. 1987 Mar;66(3):440-6. Abstract

74. Vogh BP, Langham MR Jr. The effect of furosemide and bumetanide on cerebrospinal fluid formation. Brain Res. 1981 Sep 21;221(1):171-83. Abstract

75. Buhrley LE, Reed DJ. The effect of furosemide on sodium-22 uptake into cerebrospinal fluid and brain. Exp Brain Res. 1972 Apr 27;14(5):503-10. Abstract

76. Schoeman JF. Childhood pseudotumor cerebri: clinical and intracranial pressure response to acetazolamide and furosemide treatment in a case series. J Child Neurol. 1994 Apr;9(2):130-4. Abstract

77. Schoeman J, Donald P, van Zyl L, et al. Tuberculous hydrocephalus: comparison of different treatments with regard to ICP, ventricular size and clinical outcome. Dev Med Child Neurol. 1991 May;33(5):396-405. Abstract

78. Celebisoy N, Gokcay F, Sirin H, et al. Treatment of idiopathic intracranial hypertension: topiramate vs acetazolamide, an open-label study. Acta Neurol Scand. 2007 Nov;116(5):322-7. Abstract

79. European Medicines Agency. European Medicines Agency recommends changes to the use of metoclopramide. July 2013 [internet publication].Full text

80. Eggenberger ER, Miller NR, Vitale S. Lumboperitoneal shunt for the treatment of pseudotumor cerebri. Neurology. 1996 Jun;46(6):1524-30. Abstract

81. Rosenberg M, Smith C, Beck R, et al. The efficacy of shunting procedures in pseudotumor cerebri (abstract). Neurology. 1989;39(suppl 1):S209.

82. Johnston I, Besser M, Morgan MK. Cerebrospinal fluid diversion in the treatment of benign intracranial hypertension. J Neurosurg. 1988 Aug;69(2):195-202. Abstract

83. Burgett RA, Purvin VA, Kawasaki A. Lumboperitoneal shunting for pseudotumor cerebri. Neurology. 1997 Sep;49(3):734-9. Abstract

84. McGirt MJ, Woodworth G, Thomas G, et al. Cerebrospinal fluid shunt placement for pseudotumor cerebri-associated intractable headache: predictors of treatment response and an analysis of long-term outcomes. J Neurosurg. 2004 Oct;101(4):627-32. Abstract

85. Sinclair AJ, Kuruvath S, Sen D, et al. Is cerebrospinal fluid shunting in idiopathic intracranial hypertension worthwhile? A 10-year review. Cephalalgia. 2011 Dec;31(16):1627-33. Abstract

86. Goh KY, Schatz NJ, Glaser JS. Optic nerve sheath fenestration for pseudotumor cerebri. J Neuroophthalmol. 1997 Jun;17(2):86-91. Abstract

87. Acheson JF, Green WT, Sanders MD. Optic nerve sheath decompression for the treatment of visual failure in chronic raised intracranial pressure. J Neurol Neurosurg Psychiatry. 1994 Nov;57(11):1426-9.Full text  Abstract

88. Plotnik JL, Kosmorsky GS. Operative complications of optic nerve sheath decompression. Ophthalmology. 1993 May;100(5):683-90. Abstract

89. Rizzo JF 3rd, Lessell S. Choroidal infarction after optic nerve sheath fenestration. Ophthalmology. 1994 Sep;101(9):1622-6. Abstract

90. Spoor TC, McHenry JG. Long-term effectiveness of optic nerve sheath decompression for pseudotumor cerebri. Arch Ophthalmol. 1993 May;111(5):632-5. Abstract

91. Fonseca PL, Rigamonti D, Miller NR, et al. Visual outcomes of surgical intervention for pseudotumour cerebri: optic nerve sheath fenestration versus cerebrospinal fluid diversion. Br J Ophthalmol. 2014 Oct;98(10):1360-3. Abstract

92. Huang LC, Winter TW, Herro AM, et al. Ventriculoperitoneal shunt as a treatment of visual loss in idiopathic intracranial hypertension. J Neuroophthalmol. 2014 Sep;34(3):223-8. Abstract

93. Niotakis G, Grigoratos D, Chandler C, et al. CSF diversion in refractory idiopathic intracranial hypertension: single-centre experience and review of efficacy. Childs Nerv Syst. 2013 Feb;29(2):263-7. Abstract

94. Rizzo JL, Lam KV, Wall M, et al. Perimetry, retinal nerve fiber layer thickness and papilledema grade after cerebrospinal fluid shunting in patients with idiopathic intracranial hypertension. J Neuroophthalmol. 2015 Mar;35(1):22-5. Abstract

95. Wall M, Johnson CA, Kutzko KE, et al. Long- and short-term variability of automated perimetry results in patients with optic neuritis and healthy subjects. Arch Ophthalmol. 1998 Jan;116(1):53-61. Abstract

96. Digre KB, Varner MW, Corbett JJ. Pseudotumor cerebri and pregnancy. Neurology. 1984 Jun;34(6):721-9. Abstract

97. Lee AG, Pless M, Falardeau J, et al. The use of acetazolamide in idiopathic intracranial hypertension during pregnancy. Am J Ophthalmol. 2005 May;139(5):855-9. Abstract

98. Thurtell MJ, Wall M. Idiopathic intracranial hypertension (pseudotumor cerebri): recognition, treatment, and ongoing management. Curr Treat Options Neurol. 2013 Feb;15(1):1-12.Full text  Abstract

99. Tang RA, Dorotheo EU, Schiffman JS, et al. Medical and surgical management of idiopathic intracranial hypertension in pregnancy. Curr Neurol Neurosci Rep. 2004 Sep;4(5):398-409. Abstract

100. Karmaniolou I, Petropoulos G, Theodoraki K. Management of idiopathic intracranial hypertension in parturients: anesthetic considerations. Can J Anaesth. 2011 Jul;58(7):650. Abstract

101. Friedman DI. Cerebral venous pressure, intra-abdominal pressure, and dural venous sinus stenting in idiopathic intracranial hypertension. J Neuroophthalmol. 2006;26:61-64. Abstract

102. Kabanovski A, Kisilevsky E, Yang Y, et al. Dural venous sinus stenting in the treatment of idiopathic intracranial hypertension: a systematic review and critique of literature. Surv Ophthalmol. 2022 Jan-Feb;67(1):271-87. Abstract

103. Xu W, Prime Z, Papchenko T, et al. Long term outcomes of idiopathic intracranial hypertension: observational study and literature review. Clin Neurol Neurosurg. 2021 Jan 5;205:106463. Abstract

104. Bruce BB, Kedar S, Van Stavern GP, et al. Idiopathic intracranial hypertension in men. Neurology. 2009 Jan 27;72(4):304-9.Full text  Abstract

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