Resumo
Definição
História e exame físico
Principais fatores diagnósticos
- variable onset
- pink, red, or blue color
- rapid growth
- variable compressibility
- flat or nodular character
Outros fatores diagnósticos
- islands of normal skin
- ulceration and bleeding
- warmth
- history of low birth weight
- variable pain
- associated defects
- beard distribution and stridor
- lumbosacral location
- multiple lesions
- poor infantile feeding, failure to gain weight
- high-output cardiac failure
Fatores de risco
- low birth weight
- birth prematurity
- white ethnicity
- female sex
- maternal multiple gestation
- advanced maternal age
- chorionic villus sampling
Investigações diagnósticas
Primeiras investigações a serem solicitadas
- Doppler ultrasound of hemangioma
Investigações a serem consideradas
- MRI (without and with IV contrast) of hemangioma
- biopsy of lesion
Algoritmo de tratamento
asymptomatic
with functional impairment or cosmetic disfigurement
Colaboradores
Autores
Kari L. Martin, MD
Associate Professor of Dermatology & Child Health
Pediatric Dermatology
University of Missouri – Columbia
Columbia
MO
Declarações
KLM is an investigator in clinical trials with Scioderm, Lilly, and Durata; payments were received by her institution for these trials. None of these are relevant to this topic.
Agradecimentos
Dr Kari L. Martin would like to gratefully acknowledge Dr Tobian Muir, Dr Ingrid Polcari, Dr Annette Wagner, and Dr Carla T. Lee, the previous contributors to this topic.
Declarações
TM, IP, and CTL declare that they have no competing interests. AW: none disclosed.
Revisores
Elena Pope, MD
Head
Department of Dermatology
The Hospital for Sick Children
Toronto
Ontario
Canada
Declarações
EP is an author of a number of references cited in this topic.
Elisabeth Higgins, MD
Consultant Dermatologist
King's College Hospital
London
UK
Declarações
EH declares that she has no competing interests.
Iona Friedan, MD
Professor of Clinical Dermatology and Pediatrics
University of California San Francisco
San Francisco
CA
Declarações
IF is a consultant for Pierre Fabre Dermatology, which is involved in clinical trials of propranolol for hemangiomas. IF is an author of a number of references cited in this topic.
Peer reviewer acknowledgements
BMJ Best Practice topics are updated on a rolling basis in line with developments in evidence and guidance. The peer reviewers listed here have reviewed the content at least once during the history of the topic.
Disclosures
Peer reviewer affiliations and disclosures pertain to the time of the review.
Referências
Principais artigos
Krowchuk DP, Frieden IJ, Mancini AJ, et al. Clinical practice guideline for the management of infantile hemangiomas. Pediatrics. 2019 Jan;143(1): e20183475.Texto completo Resumo
Darrow DH, Greene AK, Mancini AJ, et al. Diagnosis and management of infantile hemangioma. Pediatrics. 2015 Oct;136(4):e1060-104.Texto completo Resumo
Krowchuk DP, Frieden IJ, Mancini AJ, et al. Clinical practice guideline for the management of infantile hemangiomas. Pediatrics. 2019 Jan;143(1): e20183475.Texto completo Resumo
Artigos de referência
Uma lista completa das fontes referenciadas neste tópico está disponível para os usuários com acesso total ao BMJ Best Practice.
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