Most clinically non-functional pituitary adenomas (CNFPAs) present late because they either do not secrete any hormones or they secrete functional hormones inefficiently. They rarely produce intact glycoprotein follicle-stimulating hormone (FSH) and luteinising hormone (LH), but more commonly produce varying combinations of either FSH beta subunit and/or LH beta subunit along with the common alpha subunit.[38][39] Mean age of presentation is 50 to 55 years.[40]

BMJ Best Practice is an evidence-based point of care tool for healthcare practitioners.

To continue reading and access all of BMJ Best Practice's pages you'll need to log in or start a free trial.

You can access through your institution if your hospital, university, trust or other institution provides access to BMJ Best Practice through either OpenAthens or Shibboleth.

Use of this content is subject to our disclaimer