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Fibrocystic breasts

Última revisão: 18 Aug 2025
Última atualização: 17 Nov 2023

Resumo

Definição

History and exam

Key diagnostic factors

  • presence of risk factors
  • mastalgia
  • diffuse symmetrical lumpiness through both breasts
Full details

Other diagnostic factors

  • age 30 to 50 years
  • nipple discharge
  • palpable breast mass
Full details

Risk factors

  • late-onset menopause
  • later age at first childbirth
  • nulliparity
  • obesity
  • oestrogen replacement therapy
Full details

Diagnostic investigations

1st investigations to order

  • mammography
  • breast ultrasound
Full details

Investigations to consider

  • cyst aspiration
  • breast biopsy
Full details

Treatment algorithm

ONGOING

mastalgia

nipple discharge

Contributors

Authors

Sonia Sugg, MD

Professor of Surgery

Division of Surgical Oncology and Endocrine Surgery

University of Iowa Hospitals and Clinics

Iowa City

IA

Disclosures

SS declares that she has no competing interests.

Ingrid Lizarraga, MBBS, FACS

Clinical Associate Professor

Division of Surgical Oncology and Endocrine Surgery

University of Iowa Hospitals and Clinics

Iowa City

IA

Раскрытие информации

IL declares that she has no competing interests.

Выражение благодарностей

Dr Sonia Sugg and Dr Ingrid Lizarraga would like to gratefully acknowledge Dr Sophia Fu, Dr Sarah E. Colwick, Dr Hernan I. Vargas, Dr Carol Scott-Connor, Dr Anjali Thawani, and Dr Jesse Dirksen, the previous contributors to this topic. SEC, HIV, CSC, AT and JD declare that they have no competing interests.

Раскрытие информации

SF, SEC, HIV, CSC, AT, and JD declared that they had no competing interests.

Рецензенты

Fred Dirbas, MD

Assistant Professor of Surgical Oncology

Stanford University

Stanford

CA

Раскрытие информации

FD declares that he has no competing interests.

Justin Stebbing, MA, MRCP, MRCPath, PhD

Consultant Medical Oncologist/Senior Lecturer

Imperial College Healthcare NHS Trust

Charing Cross Hospital

London

UK

Раскрытие информации

JS declares that he has no competing interests.

Peer reviewer acknowledgements

BMJ Best Practice topics are updated on a rolling basis in line with developments in evidence and guidance. The peer reviewers listed here have reviewed the content at least once during the history of the topic.

Disclosures

Peer reviewer affiliations and disclosures pertain to the time of the review.

Список литературы

Our in-house evidence and editorial teams collaborate with international expert contributors and peer reviewers to ensure that we provide access to the most clinically relevant information possible.

Основные статьи

Marchant DJ. Benign breast disease. Obstet Gynecol Clin North Am. 2002 Mar;29(1):1-20. Аннотация

Santen RJ, Mansel R. Benign breast disorders. N Engl J Med. 2005 Jul 21;353(3):275-85. Аннотация

Love SM, Gelman RS, Silen W. Sounding board. Fibrocystic "disease" of the breast--a nondisease? N Eng J Med. 1982 Oct 14;307(16):1010-4. Аннотация

Dupont WD, Page DL. Risk factors for breast cancer in women with proliferative breast disease. N Engl J Med. 1985 Jan 17;312(3):146-51. Аннотация

Fisher B, Constantino JP, Wickerham DL, et al. Tamoxifen for prevention of breast cancer: report of the National Surgical Adjuvant Breast and Bowel Project P-1 Study. J Natl Cancer Inst. 1998 Sep 16;90(18):1371-88.Полный текст  Аннотация

Статьи, указанные как источники

A full list of sources referenced in this topic is available to users with access to all of BMJ Best Practice.
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