Search results for: huntington
Huntington disease - Treatment algorithm
/our-services/specialist-services/neuropsychiatry/occupational-therapy-for-people-with-huntingtons
Huntington disease - Approach
behavior is bad temper. 8135306 Lipe H, Schultz A, Bird TD. Risk factors for suicide in Huntingtons
Huntington disease - Guidelines
/articles/journal-of-huntingtons-disease/jhd180293 Journal of Huntington's Disease 2018 https
Huntington disease - Criteria
: clinical care and evaluation. Neurology. 1979 Jan;29(1):1-3. 8684382 Huntington Study Group. Unified
Huntington disease - Complications
Nurs. 1989 Apr;21(2):92-5. 14742590 Hamilton JM, Wolfson T, Peavy GM, et al; Huntington Study Group
Huntington disease - Emerging
://content.iospress.com/articles/journal-of-huntingtons-disease/jhd200440 A phase 3, randomized, double-blind
Images and videos
Images
Huntington disease
Life cycle in Huntington disease (HD)
Walker FO. Huntington's disease. Lancet 2007 Jan 20;369(9557):218-28. Used with permission
Huntington disease
EMG of chorea in stage I disease; recording made with standard belly tendon, surface disk electrodes over first dorsal interosseous muscle
Walker FO. Huntington's disease. Lancet 2007 Jan 20;369(9557):218-28. Used with permission
Acquired torticollis
Patient with moderate left torticollis or neck rotation, mild right laterocollis or lateral neck flexion, and mild retrocollis or neck extension
From the collection of Dr David Sommer
Acquired torticollis
Patient with severe left torticollis (note hypertrophy of right sternocleidomastoid muscle)
From the collection of Dr David Sommer
Acquired torticollis
Patient using sensory trick with reduction in dystonia severity
From the collection of Dr David Sommer
Prion disease
Changes in the basal ganglia seen in Creutzfeldt-Jakob disease. (A) Fluid-attenuated inversion recovery MRI and (B) diffusion-weighted MRI of the same patient demonstrate bilateral basal ganglia hyperintensities (arrows). There is also mild bilateral medial thalamus and pulvinar hyperintensity
From the personal collection of Dr M. Geschwind
Prion disease
Diffuse cortical ribboning (arrows) seen on (A) diffusion-weighted imaging (DWI) and less so on (B) fluid-attenuated inversion recovery (FLAIR) MRI. Both sequences show cerebral cortex gyral hyperintensities
From the personal collection of Dr M. Geschwind
Prion disease
Bilateral medial thalamus and pulvinar hyperintensity (arrowheads) on (A) fluid-attenuated inversion recovery and (B) diffusion-weighted MRI in a patient with Creutzfeldt-Jakob. This patient also has significant basal ganglia hyperintensity on both sequences (arrows)
From the personal collection of Dr M. Geschwind
Prion disease
Outline of evaluation for non-Creutzfeldt-Jakob rapidly progressive dementias workup
Memory and Aging Center, University of California, San Francisco, CA
Evaluation of memory deficit
Diagnostic algorithm for chronic onset memory deficit; bvFTD, behavioral variant frontotemporal dementia; CBD, corticobasal degeneration; FDG-PET, fluorodeoxyglucose - positron emission tomography; FTD, frontotemporal degeneration; LP, lumbar puncture; PIB-PET, Pittsburgh compound B - positron emission tomography; PNFA, progressive nonfluent aphasia; PSP, progressive supranuclear palsy
Created by Mee-Ohk Kim, MD, PhD and Michael D. Geschwind, MD, PhD; used with permission
Evaluation of memory deficit
MRI brain: shows diffuse cortical atrophy with predominant hippocampal atrophy (red arrows) in patient with Alzheimer dementia. Parietal atrophy and neocortical involvement is evident in more advanced disease (blue arrows)
From the personal collection of Michael D. Geschwind, MD, PhD; used with permission
Evaluation of memory deficit
MRI brain (T2 weighted): demonstrates symmetric hyperintensity of the bilateral medial temporal lobes (hippocampi; outlined by arrows pointing to anterior and middle of hippocampi) consistent with active inflammation in limbic encephalitis and encephalopathy. Note that hippocampi are brighter than other gray matter regions, particularly posterior cortex
From the personal collection of Michael D. Geschwind, MD, PhD; used with permission
Evaluation of memory deficit
Diagnostic algorithm for acute onset memory deficit. 1: changes in signal intensities, structural lesions on brain MRI; 2: sometimes increased signal intensities on diffusion-weighted imaging; EEG, electroencephalogram; MRI, magnetic resonance imaging
Created by Mee-Ohk Kim, MD, PhD and Michael D. Geschwind, MD, PhD; used with permission
Evaluation of memory deficit
Diagnostic algorithm for subacute onset memory deficit. 1: changes in signal intensities, structural lesions on brain MRI; 3: MRI in CJD shows cortical ribboning and/or deep nuclei restricted diffusion on diffusion-weighted imaging/apparent diffusion coefficient map; CSF biomarkers might be elevated; ADC, apparent diffusion coefficient; CJD, Creutzfeldt-Jakob disease; CSF, cerebrospinal fluid; DWI, diffusion-weighted imaging; HSV, herpes simplex virus; MRI, magnetic resonance imaging; NSE, neuron-specific enolase
Created by Mee-Ohk Kim, MD, PhD and Michael D. Geschwind, MD, PhD; used with permission
Case reports
Case reports are not necessarily evidence-based in the same way that the other content on BMJ Best Practice is. They should not be relied on to guide clinical practice. Please check the date of publication.
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