Call us today

1 (855) 458-0579

Best Evidence-Based
Clinical Decision
Support Tool

BMJ Best Practice is the only EBM tool with a dedicated Comorbidities Manager. Point-of-care guidance is uniquely structured around the patient consultation. Healthcare professionals and teams receive a tailored plan that treats the whole patient.

Please note: Within the Americas, Comorbidities access is currently limited to Canada, Latin America, and the Caribbean.

Explore Comorbidities Topics

When comorbidities are considered in the acute care setting, healthcare professionals more effectively manage their patients. This leads to better clinical outcomes, shorter hospital stays and fewer readmissions.


The Comorbidities Manager has been incorporated into 50+ topics within BMJ Best Practice, providing more than 25,500 different guideline combinations.

  • Acute appendicitis in adults
  • Acute asthma exacerbation in adults
  • Acute cervical spine trauma in adults
  • Acute cholangitis
  • Acute cholecystitis
  • Acute exacerbation of COPD
  • Acute heart failure
  • Acute kidney injury
  • Acute pancreatitis
  • Acute pyelonephritis
  • Alcohol withdrawal
  • Anaphylaxis
  • Bacterial meningitis in adults
  • Carbon monoxide poisoning
  • Cellulitis and erysipelas
  • Cholelithiasis (gallstones)
  • Community-acquired pneumonia


  • Coronavirus disease 2019 (COVID-19)
  • Diabetic ketoacidosis
  • Epistaxis
  • Heat stroke in adults
  • Hip fracture
  • Hospital-acquired pneumonia
  • Hyperosmolar hyperglycaemic state
  • Ischaemic stroke
  • Large bowel obstruction
  • Mild traumatic brain injury
  • Nephrolithiasis
  • New-onset atrial fibrillation
  • Non-ST-elevation myocardial infarction
  • Osteomyelitis
  • Paracetamol overdose in adults
  • Peptic ulcer disease


  • Pneumothorax
  • Pulmonary embolism
  • Salicylate poisoning
  • Schizophrenia
  • Sepsis in adults
  • Septic arthritis
  • Shock
  • Skull fractures
  • Small bowel obstruction
  • ST-elevation myocardial infarction
  • Status epilepticus
  • Stroke due to spontaneous intracerebral haemorrhage
  • Subarachnoid haemorrhage
  • Transient ischaemic attack
  • Unstable angina
  • Urinary tract infections in women
  • Viral gastroenteritis in adults

Chronic obstructive pulmonary disease (COPD) is a long-term condition that affects a patient’s lungs. It causes the airways to become narrow, trapping air in the chest and making it difficult to exhale. An acute exacerbation of COPD (AECOPD) is a type of clinical diagnosis that occurs when patients with COPD experience a sustained increase in dyspnea, sputum production, and or cough. It is important to note that comorbidities have a significant impact on the treatment considerations for AECOPD.

Test the Comorbidities Manager for evidence-based guidance on symptom evaluation, test ordering and treatment.

Show Comorbidities tool on Acute Exacerbation of COPD


The presence of two chronic conditions alongside COVID-19 may increase the chance of hospitalization and/or the risk of death. As reported by the Public Health Agency of Canada, 90% of COVID-19 related deaths between March and July 2020 occurred among those with a pre-existing comorbidity.

Test the Comorbidities Manager to see how our clinical decision support tool can help professionals in COVID-19 care, management and severity assessment.

Show Comorbidities tool on COVID-19


Canadian adults suffer from multiple chronic conditions


of patients admitted to the ICU with COVID-19 suffer from comorbidities


of healthcare professionals would consider using this tool to improve the care that they give in the future.

Watch the Comorbidities Manager in action

An 82-year-old man comes to the ER with an acute exacerbation of COPD. See how the Comorbidities Manager prompts the clinician to consider his Type 2 Diabetes alongside his acute condition. The result is a tailored treatment plan based on evidence and expert opinion.

Offline access = Real time support

BMJ Best Practice is device responsive and works across a wide variety of mobile computing devices and personal digital assistants. Our complimentary app also provides convenient offline access to the entire product and additional tools, such as the ‘Look Up’ command and split screen.

Comorbidities Renders Across Devices

Ranked one of the best clinical decision support tools for health professionals worldwide*

BMJ Best Practice provides step-by-step guidance on symptom evaluation, diagnosis, treatment, follow up and future prevention. Updated daily.

Review the benefits for healthcare professionals, including clinicians, pharmacists and medical students.

*Journal of Medical Internet Research


Clinical research and guidelines are based on the latest evidence-based research.

CME Points

Earn credits while searching for answers to your clinical questions.


The right information, whenever and wherever you need it.


What are others saying?

“BMJ Best Practice Comorbidities allows clinicians to look at the key focal diagnosis and see how to consider the other impacting chronic conditions. This is why it’s important to promote BMJ Best Practice Comorbidities to Residents and Advanced Nurse Practitioners.”

Tim Mossad
Consultant in Emergency Medicine

“BMJ Best Practice Comorbidities provides a logical approach to an area that could become hugely complex.
When I chose a single comorbidity, the information was relevant, useful, and pragmatic.”

Dr Colin Mitchell
Consultant Geriatrician and Head of Specialty

“The tools and content provided on the [BMJ Best Practice] platform are reliable and easy to navigate for the end user.”

– The Charleston Advisor, January 2021

Jamie Saragossi
Health Sciences Library, Stony Brook University, New York

“Provides easily accessible evidence based management plan that facilitates more confident and precise decision making”


Tracian James-Goulbourne
Resident Physician, SUNY Downstate Medical Center

“Helps find the right answer quickly rather than having to appraise and synthesize information from multiple sources. Point form layout, makes it easier to navigate.”

Ani Orchanian-Cheff
Information Specialist, University Health Network