Last reviewed: November 2017
Last updated: November  2017

Summary

Differentials

Common

  • Allergy to food or drug
  • Insect bites or stings
  • Antibiotic, anticonvulsant, or allopurinol adverse reaction
  • Chemotherapy
  • Enterovirus and echovirus infection
  • Fifth disease (erythema infectiosum)
  • Roseola infantum (sixth disease)
  • EBV infection (infectious mononucleosis)
  • Cytomegalovirus infection
  • Scarlet fever

Uncommon

  • Toxic epidermal necrolysis or Stevens-Johnson syndrome
  • Drug reaction with eosinophilia and systemic symptoms (DRESS)
  • Erythema multiforme
  • Systemic hypersensitivity syndrome
  • HIV-seroconversion exanthema
  • Acute hepatitis B virus infection
  • Acute hepatitis C virus infection
  • Rubella (German measles)
  • Rubeola (measles)
  • Meningococcaemia
  • Staphylococcal scalded skin syndrome
  • Toxic shock syndrome (Staphylococcus exotoxin)
  • Rocky Mountain spotted fever or Mediterranean spotted fever
  • Acute graft-versus-host disease (aGVHD)
  • Kawasaki disease (mucocutaneous lymph node syndrome)
  • Juvenile-onset or adult-onset Still disease
  • Syphilis (secondary)
  • Ebola virus infection
  • Zika virus infection
  • Chikungunya virus infection

Contributors

Authors VIEW ALL

Dermatologist

Kaiser Permanente

Falls Church

VA

Disclosures

MN declares that he has no competing interests.

Dr Mark Naftanel would like to gratefully acknowledge Dr Hobart W. Walling, a previous contributor to this monograph. HWW declares that he has no competing interests.

Peer reviewers VIEW ALL

Clinical Assistant Professor

University of Iowa College of Medicine

Iowa City

IA

Disclosures

BS declares that he has no competing interests.

Dermatologist

Town Square Dermatology

Coralville

IA

Disclosures

KS declares that she has no competing interests.

Use of this content is subject to our disclaimer