Last reviewed: November 2017
Last updated: April  2017

Summary

Definition

History and exam

Key diagnostic factors

  • presence of risk factors
  • recent upper respiratory tract infection
  • dyspnoea
  • cough
  • expiratory wheezes
  • nasal polyposis

Risk factors

  • FHx
  • allergens
  • atopic history
  • nasal polyposis
  • obesity
  • gastro-oesophageal reflux

Diagnostic investigations

1st investigations to order

  • FEV1/FVC ratio
  • FEV1
  • peak expiratory flow rate (PEFR)
  • CXR
  • FBC
Full details

Investigations to consider

  • bronchial challenge test
  • immunoassay for allergen-specific IgE
  • skin prick allergy testing
Full details

Emerging tests

  • exhaled nitric oxide (eNO)
  • sputum eosinophilia
Full details

Treatment algorithm

Contributors

Authors VIEW ALL

Consultant

Emergency Department

National University Hospital

Singapore

Disclosures

II declares that she has no competing interests.

Head and Consultant

Division of Respiratory and Critical Care Medicine

National University Hospital

Singapore

Disclosures

KCS declares that he has no competing interests.

Dr Irwani Ibrahim and Dr Kay Choong See would like to gratefully acknowledge Dr Francis Thien and Dr Catherine Weiler, previous contributors to this monograph. FT and CW declare that they have no competing interests.

Peer reviewers VIEW ALL

Clinical Director

Division of Allergy and Inflammation

Beth Israel Deaconess Medical Center/Harvard Medical School

Boston

MA

Disclosures

JS is a consultant for Aventis, GSK, and Novartis/Genentech; is on the Speakers Bureau for Merck, Aventis, GSK, AstraZeneca, Pfizer, Novartis/Genentech, Inspire, and UCB; has had research sponsored by GSK; is an expert witness at Haemonetics; and has received publication honorarium at Emedicine.

Research Manager

Imperial College Healthcare Trust

NHLI Airways Division

Imperial College London (Honorary) Respiratory Research

Chest & Allergy

St Mary's Hospital

London

UK

Disclosures

SMSS declares that she has no competing interests.

Professor of Respiratory Medicine

Respiratory Medicine Section

Division of Immunology, Infection & Inflammation

University of Glasgow

Glasgow

UK

Disclosures

NT declares that he has no competing interests.

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