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Psoriatic arthritis

Last reviewed: 13 Nov 2025
Last updated: 28 Jul 2023

小结

定义

病史和体格检查

关键诊断因素

  • personal or family history of psoriasis
  • joint pain and stiffness
  • peripheral arthritis
  • dactylitis
  • history of scalp or nail problems
完整详情

其他诊断因素

  • enthesitis
  • spinal stiffness
  • reduction of cervical spine mobility
  • uveitis
  • inflammatory bowel disease
完整详情

危险因素

  • psoriasis
  • family history of psoriasis or psoriatic arthritis
  • history of joint or tendon trauma
  • infection
  • smoking
完整详情

诊断性检查

首要检查

  • plain film x-rays of the hands and feet
  • erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP)
  • rheumatoid factor
  • anti-cyclic citrullinated peptide (anti-CCP) antibody
  • lipid profile
  • fasting blood glucose
  • uric acid level
  • synovial fluid aspiration and analysis
完整详情

需考虑的检查

  • plain film x-rays of the spine and pelvis
  • MRI scan of sacroiliac joints
完整详情

新兴检查

  • joint ultrasound

治疗流程

急症处理

peripheral arthritis

axial disease

enthesitis

dactylitis

撰稿人

作者

Siba P. Raychaudhuri, MD, FACP, FACR

Professor

Director, Department of Medicine/ Rheumatology, Allergy, and Clinical Immunology

University of California Davis School of Medicine

Sacramento

CA

利益声明

SPR declares that he has received research grants, prepared research papers, and attended board meetings for Sun Pharmacy, AbbVie Pharmacy, Novartis Pharma, Johnson and Johnson, the National Psoriasis Foundation, and the US National Institutes of Health (NIH). SPR is the author of some of the references cited in this topic.

鸣谢

Dr Siba P. Raychaudhuri would like to gratefully acknowledge Dr Clement J. Michet, previous contributor to this topic.

利益声明

CJM is an author of a reference cited in this topic.

同行评议者

Philip S. Helliwell, MD, PhD

Senior Lecturer in Rheumatology

University of Leeds

Leeds

UK

利益声明

PSH is an author of some references cited in this topic.

Luis R. Espinoza, MD

Professor and Chief

Section of Rheumatology

Department of Internal Medicine

LSU Health Sciences Center

New Orleans

LA

利益声明

LRE declares that he has no competing interests.

William J. Taylor, PhD, MBChB, FAFRM, FRACP

Associate Professor

Department of Medicine

University of Otago, Wellington

Wellington

New Zealand

利益声明

WJT is an author of some references cited in this topic.

Peer reviewer acknowledgements

BMJ Best Practice topics are updated on a rolling basis in line with developments in evidence and guidance. The peer reviewers listed here have reviewed the content at least once during the history of the topic.

Disclosures

Peer reviewer affiliations and disclosures pertain to the time of the review.

参考文献

Our in-house evidence and editorial teams collaborate with international expert contributors and peer reviewers to ensure that we provide access to the most clinically relevant information possible.

关键文献

Singh JA, Guyatt G, Ogdie A, et al. 2018 American College of Rheumatology/National Psoriasis Foundation guideline for the treatment of psoriatic arthritis. Arthritis Rheumatol. 2019 Jan;71(1):5-32.全文  摘要

Gossec L, Baraliakos X, Kerschbaumer A, et al. EULAR recommendations for the management of psoriatic arthritis with pharmacological therapies: 2019 update. Ann Rheum Dis. 2020 Jun;79(6):700-12.全文  摘要

Coates LC, Soriano ER, Corp N, et al; GRAPPA Treatment Recommendations domain subcommittees. Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA): updated treatment recommendations for psoriatic arthritis 2021. Nat Rev Rheumatol. 2022 Aug;18(8):465-79.全文  摘要

参考文献

A full list of sources referenced in this topic is available to users with access to all of BMJ Best Practice.
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