Resumo
Differentials
Common
- Tuberculose (TB)
- Abscesso abdominal ou pélvico
- vírus da imunodeficiência humana (HIV)
- Rinossinusite, aguda ou crônica
- Pneumonia bacteriana
- Infecção do trato urinário
Uncommon
- Endocardite infecciosa
- Abscessos dentários
- Osteomielite
- Prostatite, aguda ou crônica
- Infecção por citomegalovírus
- Infecção por vírus Epstein-Barr
- Doença do coronavírus 2019 (COVID-19)
- Febre reumática
- Doença de Lyme
- Leucemia mieloide crônica
- Linfoma de Hodgkin
- Linfoma não Hodgkin
- Carcinoma metastático, primário desconhecido
- Câncer renal
- Síndrome mielodisplásica
- Doença de Still de início tardio
- Polimialgia reumática
- Arterite de células gigantes
- Lúpus eritematoso sistêmico
- Doença de Crohn
- Colite ulcerativa
- Artrite reumatoide
- Artrite reativa
- Febre induzida por medicamento
- Complicada, cirrose
- Hepatite
- Trombose venosa profunda
- Sarcoidose
- Síndromes de febre periódica
- Malária
- Febre tifoide
- Febre maculosa das Montanhas Rochosas
- Ascaríase
- Tularemia
- Brucelose
- Psitacose
- Febre Q
- Feocromocitoma
- Hipertireoidismo
- Síndrome de Munchausen
- Febre da dengue
Contributors
Authors
William F. Wright,, DO, MPH
Assistant Professor
Division of Infectious Diseases, Department of Medicine
Johns Hopkins University School of Medicine
Baltimore
MD
Disclosures
WFW declares that he has no competing interests. WFW is an author of references cited in this topic.
Paul G. Auwaerter, MD
Professor
Division of Infectious Diseases, Department of MedicineThe Sherrilyn and Ken Fisher Center for Environmental Infectious Diseases
Johns Hopkins University School of Medicine
Baltimore
MD
Disclosures
PGA declares that he has no competing interests. PGA is an author of references cited in this topic.
Acknowledgements
Dr William F. Wright and Dr Paul G. Auwaerter would like to gratefully acknowledge Dr Roth and Dr Basello, previous contributors to this topic.
Peer reviewers
Kevin P. High, MD, MS, MACP, FIDSA
Professor of Medicine
Wake Forest University School of Medicine
Vice Chief Academic Officer, aLHS, Advocate Health
Winston-Salem
NC
Disclosures
KPH declares that he has no competing interests.
Peer reviewer acknowledgements
BMJ Best Practice topics are updated on a rolling basis in line with developments in evidence and guidance. The peer reviewers listed here have reviewed the content at least once during the history of the topic.
Disclosures
Peer reviewer affiliations and disclosures pertain to the time of the review.
References
Key articles
Haidar G, Singh N. Fever of unknown origin. N Engl J Med. 2022 Feb 3;386(5):463-77. Abstract
Cunha BA, Lortholary O, Cunha CB. Fever of unknown origin: a clinical approach. Am J Med. 2015 Oct;128(10):1138.e1-1138.e15.Full text Abstract
Wright WF, Auwaerter PG. Fever and fever of unknown origin: review, recent advances, and lingering dogma. Open Forum Infect Dis. 2020 May;7(5):ofaa132.Full text Abstract
Reference articles
A full list of sources referenced in this topic is available to users with access to all of BMJ Best Practice.
Guidelines
- Pyrexia of unknown origin
More Guidelines
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