When viewing this topic in a different language, you may notice some differences in the way the content is structured, but it still reflects the latest evidence-based guidance.

Short bowel syndrome

Last reviewed: 13 Feb 2025
Last updated: 29 Jun 2022

Summary

Definition

History and exam

Key diagnostic factors

  • weight loss
  • diarrhea
  • volume depletion
  • peripheral or presacral edema
Full details

Other diagnostic factors

  • fatigue
  • postprandial epigastric or right upper quadrant abdominal pain
  • dysuria or renal colic
  • abnormal neurologic examination
  • jaundice and pruritus
  • dermatologic signs
  • night blindness
  • motor weakness or altered gait
  • proximal muscle weakness
  • excessive bleeding
  • confusion
Full details

Risk factors

  • bowel resection
  • extensive abdominal radiation injury
  • gastroschisis
Full details

诊断性检查

首要检查

  • CBC
  • serum electrolytes
  • BUN and creatinine
  • serum albumin
  • serum calcium, zinc, selenium, folate
  • vitamins A, B1, B2, B6, B12, C, D, and E
  • methylmalonic acid (MMA)
  • INR
完整详情

需考虑的检查

  • serum hepatic aminotransferases, alkaline phosphatase, and bilirubin (total and direct)
  • urine analysis
  • serum D-lactate
  • fecal fat quantification
  • upper gastrointestinal contrast series
  • Dual-energy x-ray absorptiometry (DXA) scan
  • abdominal ultrasound
  • CT abdomen
完整详情

治疗流程

急症处理

jejunoileocolic anastomosis

jejunoileal anastomosis with fully resected colon

end jejunostomy or duodenostomy

持续性治疗

all patients

撰稿人

作者

Alan Buchman, MD, MSPH, FACP, FACG, FACN, AGAF
Alan Buchman

Medical Director, Gastroenterology

Anthem Health

Indianapolis

IN

利益声明

AB is an author of references cited in this topic.

鸣谢

Dr Alan Buchman would like to gratefully acknowledge Dr Michael Roth, a previous contributor to this topic. MR is an author of a reference cited in this topic.

同行评议者

Marian F. Winkler, PhD RD

Professor of Surgery

Surgical Nutrition Specialist

Alpert Medical School of Brown University and Rhode Island Hospital

Providence

RI

利益声明

MFW declares that she has no competing interests.

Jonathan Shaffer, MBBS

Hospital Dean

Intestinal Failure Unit

Hope Hospital

Salford

Manchester

UK

利益声明

Not disclosed. JS is the author of references cited in this topic.

内容使用需遵循免责声明