Last reviewed: 2 Feb 2021
Last updated: 24 Mar 2020
Summary
Definition
History and exam
Key diagnostic factors
- close contact with other infected individuals
- bright red macular erythema of the bilateral cheeks with sparing of the nasal ridge and perioral areas
- erythematous macules and papules evolving into lacy reticular erythema, most notable on the extremities
- immunodeficiency
Other diagnostic factors
- arthralgia/arthritis
- prodrome (fever, headache, pharyngitis, coryza, abdominal pain)
- symptoms of anemia
Risk factors
- close contact with other infected individuals
- immunodeficiency
- age 6 to 10 years
Diagnostic investigations
Treatment algorithm
Contributors
Authors
Associate Professor of Dermatology & Child Health
Pediatric Dermatology
University of Missouri - Columbia
Columbia
MO
Disclosures
KLM declares that she has no competing interests.
Dr Kari L. Martin would like to gratefully acknowledge Dr Christine T. Lauren, Dr Jon Dyer, and Dr Jennifer Holman, the previous contributors to this topic. CTL, JD, and JH declare that they have no competing interests.
Peer reviewers
Professor
Department of Pathology and Laboratory Medicine
Children's and Women's Health Centre of British Columbia
Vancouver
Canada
Disclosures
NC declares that he has no competing interests.
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