When viewing this topic in a different language, you may notice some differences in the way the content is structured, but it still reflects the latest evidence-based guidance.

Erythema infectiosum

Última revisão: 18 Aug 2025
Última atualização: 15 Nov 2024

Resumo

Definição

História e exame físico

Principais fatores diagnósticos

  • close contact with other infected individuals
  • bright red macular erythema of the bilateral cheeks with sparing of the nasal ridge and perioral areas
  • erythematous macules and papules evolving into lacy reticular erythema, most notable on the extremities
  • immunodeficiency
Detalhes completos

Outros fatores diagnósticos

  • arthralgia/arthritis
  • prodrome (fever, headache, pharyngitis, coryza, abdominal pain)
  • symptoms of anemia
Detalhes completos

Fatores de risco

  • close contact with other infected individuals
  • immunodeficiency
  • age 6 to 10 years
Detalhes completos

Investigações diagnósticas

Primeiras investigações a serem solicitadas

  • clinical diagnosis
Detalhes completos

Investigações a serem consideradas

  • CBC
  • reticulocyte count
  • serology
  • DNA assays
Detalhes completos

Algoritmo de tratamento

AGUDA

fever

secondary arthritis

CONTÍNUA

persistent (>3 weeks) parvovirus B19 infection

Colaboradores

Autores

Joseph M. Lam, MD

Clinical Associate Professor, Department of Pediatrics

Associate Member, Department of Dermatology and Skin Sciences

University of British Columbia, BC Children’s Hospital

Vancouver

BC

Canada

Declarações

JML declares that he has no relevant competing interests.

Alexander K. C. Leung, MD

Department of Pediatrics

The University of Calgary, Alberta Children's Hospital

Calgary

Alberta

Canada

Declarações

AKCL declares that he has no relevant competing interests.

Agradecimentos

Dr Joseph M. Lam and Dr Alexander Leung would like to gratefully acknowledge Dr Kari L. Martin, Dr Christine T. Lauren, Dr Jon Dyer, and Dr Jennifer Holman, the previous contributors to this topic. KLM has served as a board member for Women's Dermatologic Society and American Contact Dermatitis Society. CTL, JD, and JH declare that they have no competing interests.

Peer reviewers

Nevio Cimolai, MD

Professor

Department of Pathology and Laboratory Medicine

Children's and Women's Health Centre of British Columbia

Vancouver

Canada

Disclosures

NC declares that he has no competing interests.

Peer reviewer acknowledgements

BMJ Best Practice topics are updated on a rolling basis in line with developments in evidence and guidance. The peer reviewers listed here have reviewed the content at least once during the history of the topic.

Disclosures

Peer reviewer affiliations and disclosures pertain to the time of the review.

References

Our in-house evidence and editorial teams collaborate with international expert contributors and peer reviewers to ensure that we provide access to the most clinically relevant information possible.

Key articles

Young NS, Brown KE. Parvovirus B19. N Engl J Med. 2004;350:586-597. Abstract

UK Health Security Agency. Parvovirus B19: guidance, data and analysis. Aug 2024 [internet publication].Full text

Cherry JD. Parvovirus infections in children and adults. Adv Pediatr. 1999;46:245-69. Abstract

Kimberlin DW, Banerjee R, Barnett ED, et al. Red book: 2024-2027 report of the Committee on Infectious Diseases. 33rd ed. Elk Grove Village, IL: American Academy of Pediatrics; 2024.

Centers for Disease Control and prevention. Parvovirus B19 and fifth disease. Nov 2019 [internet publication].Full text

Reference articles

A full list of sources referenced in this topic is available to users with access to all of BMJ Best Practice.

Use of this content is subject to our disclaimer