Evaluation of seronegative arthritis

Last reviewed: 12 Nov 2024
Last updated: 14 Oct 2021

Summary

Differentials

Common

  • Ankylosing spondylitis
  • Psoriatic arthritis
  • Reactive arthritis
  • Undifferentiated spondyloarthropathy
  • Calcium pyrophosphate deposition disease (CPPD)
  • Gout
  • Polymyalgia rheumatica
  • Osteoarthritis
  • Rheumatoid arthritis (RA)
  • Systemic lupus erythematosus
  • Septic arthritis
  • Bacterial endocarditis
  • Viral arthritis
Full details

Uncommon

  • Enteropathic arthritis
  • Remitting seronegative symmetrical synovitis with pitting edema syndrome
  • Sarcoidosis
  • Juvenile-onset or adult-onset idiopathic arthritis
  • Overlap syndrome
  • Sjogren syndrome
  • Scleroderma
  • Polymyositis
  • Dermatomyositis
  • Systemic vasculitis
  • Gonococcal arthritis
  • Rheumatic fever
  • Lyme disease
  • Whipple disease
  • Tuberculous arthritis
  • Paraneoplastic arthritis
  • Neoplastic carcinomatosis
Full details

Contributors

Authors

Gurjit S. Kaeley, MBBS, MRCP

Professor of Medicine

Chief, Division of Rheumatology and Clinical Immunology

Medical Director, Musculoskeletal Ultrasound Program

Program Director, Rheumatology Fellowship

University of Florida College of Medicine - Jacksonville

Jacksonville

FL

Disclosures

GSK declares that he has no competing interests.

Peer reviewers

Jacob Aelion, MD

Clinical Professor of Medicine

University of Tennessee Health Science Center

Memphis

TN

Disclosures

JA is a consultant and on the speakers' roster for Abbott, Amgen, Forrest, Roche, Takeda, UCB, Wyeth. JA has received research funding from NIH and the National Psoriasis Foundation.

William Taylor, PhD, MBChB, FAFRM, FRACP

Associate Professor; Head

Rehabilitation Teaching and Research Unit

Department of Medicine

University of Otago

Wellington

New Zealand

Disclosures

WT declares that he has no competing interests.

Rod Hughes, MA, MD, FRCP

Consultant Rheumatologist

Ashford and St Peter's Hospitals NHS Trust

Chertsey

Surrey

UK

Disclosures

RH declares that he has no competing interests.

Richard Rynes, MD

Clinical Professor of Medicine

University of Washington

Seattle

WA

Disclosures

RR declared that he had no competing interests. We have since been made aware that RR is deceased.

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