Resumo
Definição
História e exame físico
Principais fatores diagnósticos
- pruritus
- violaceous, flat-topped papules or plaques
- Wickham striae
- mucosal erosions and lacy white network
- scarring alopecia
- nail involvement
Outros fatores diagnósticos
- dorsal pterygium
- history of hepatitis C (HCV)
Fatores de risco
- hepatitis C (in some patient populations)
- -308 G/A polymorphism in TNF-alpha gene
- hepatitis B vaccination
- influenza vaccination
- coronavirus disease 2019 (COVID-19) vaccination
- psychosocial stress
- oral allergens
- use of certain drugs
Investigações diagnósticas
Primeiras investigações a serem solicitadas
- clinical diagnosis
Investigações a serem consideradas
- histopathology
- hepatitis C screen
- immunofluorescence
Algoritmo de tratamento
cutaneous disease
scalp disease
oral disease
genital disease
nail disease
Colaboradores
Autores
Deepani Munidasa, MBBS, MD
Consultant Dermatologist
Department of Dermatology
Anuradhapura Teaching Hospital
Anuradhapura
Sri Lanka
Declarações
DM declares that she has no competing interests.
Agradecimentos
Dr Deepani Munidasa would like to gratefully acknowledge Dr Susan Cooper, Dr Rebecca Dunn, Dr Julia S. Lehman, Dr Megha M. Tollefson, and Dr Lawrence E. Gibson, previous contributors to this topic.
Declarações
SC is chair of the British Society for the Study of Vulval Disease and receives royalties for contributions to UpToDate. RD, JSL, MMT, and LEG declare that they have no competing interests.
Revisores
Brian Swick, MD
Clinical Assistant Professor
University of Iowa College of Medicine
Iowa City
IA
Declarações
BS declares that he has no competing interests.
David Cassarino, MD, PhD
Assistant Professor
Department of Pathology and Laboratory Medicine
University of California
Los Angeles
CA
Declarações
DC declares that he has no competing interests.
Créditos aos pareceristas
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Declarações
As afiliações e declarações dos pareceristas referem--se ao momento da revisão.
Referências
Principais artigos
American College of Obstetricians and Gynecologists. Practice bulletin no. 224: diagnosis and management of vulvar skin disorders. Jul 2020 [internet publication].Texto completo Resumo
Edwards SK, Bates CM, Lewis F, et al. 2014 UK national guideline on the management of vulval conditions. Int J STD AIDS. 2015 Aug;26(9):611-24. Resumo
Ioannides D, Vakirlis E, Kemeny L, et al. European S1 guidelines on the management of lichen planus: a cooperation of the European Dermatology Forum with the European Academy of Dermatology and Venereology. J Eur Acad Dermatol Venereol. 2020 Jul;34(7):1403-14.Texto completo Resumo
Artigos de referência
Uma lista completa das fontes referenciadas neste tópico está disponível para os usuários com acesso total ao BMJ Best Practice.

Differentials
- Lichen simplex chronicus
- Psoriasis
- Lichen planus pemphigoides
More DifferentialsGuidelines
- Diagnosis and management of vulvar skin disorders
- European S1 guidelines on the management of lichen planus
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