When viewing this topic in a different language, you may notice some differences in the way the content is structured, but it still reflects the latest evidence-based guidance.

Lichen planus

Last reviewed: 13 Feb 2025
Last updated: 20 Dec 2024

Summary

定义

病史和体格检查

关键诊断因素

  • pruritus
  • violaceous, flat-topped papules or plaques
  • Wickham striae
  • mucosal erosions and lacy white network
  • scarring alopecia
  • nail involvement
完整详情

其他诊断因素

  • dorsal pterygium
  • history of hepatitis C (HCV)
完整详情

危险因素

  • hepatitis C (in some patient populations)
  • -308 G/A polymorphism in TNF-alpha gene
  • hepatitis B vaccination
  • influenza vaccination
  • coronavirus disease 2019 (COVID-19) vaccination
  • psychosocial stress
  • oral allergens
  • use of certain drugs
完整详情

诊断性检查

首要检查

  • clinical diagnosis
完整详情

需考虑的检查

  • histopathology
  • hepatitis C screen
  • immunofluorescence
完整详情

治疗流程

急症处理

cutaneous disease

scalp disease

oral disease

genital disease

nail disease

撰稿人

作者

Deepani Munidasa, MBBS, MD

Consultant Dermatologist

Department of Dermatology

Anuradhapura Teaching Hospital

Anuradhapura

Sri Lanka

Declarações

DM declares that she has no competing interests.

Agradecimentos

Dr Deepani Munidasa would like to gratefully acknowledge Dr Susan Cooper, Dr Rebecca Dunn, Dr Julia S. Lehman, Dr Megha M. Tollefson, and Dr Lawrence E. Gibson, previous contributors to this topic.

Declarações

SC is chair of the British Society for the Study of Vulval Disease and receives royalties for contributions to UpToDate. RD, JSL, MMT, and LEG declare that they have no competing interests.

Revisores

Brian Swick, MD

Clinical Assistant Professor

University of Iowa College of Medicine

Iowa City

IA

Declarações

BS declares that he has no competing interests.

David Cassarino, MD, PhD

Assistant Professor

Department of Pathology and Laboratory Medicine

University of California

Los Angeles

CA

Declarações

DC declares that he has no competing interests.

  • Lichen planus images
  • Diagnósticos diferenciais

    • Lichen simplex chronicus
    • Psoriasis
    • Lichen planus pemphigoides
    Mais Diagnósticos diferenciais
  • Diretrizes

    • Diagnosis and management of vulvar skin disorders
    • European S1 guidelines on the management of lichen planus
    Mais Diretrizes
  • padlock-lockedConectar-se ou assinar para acessar todo o BMJ Best Practice

O uso deste conteúdo está sujeito ao nosso aviso legal