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Androgenetic alopecia

Evidence last reviewed: 10 Sep 2026
Topic last updated: 06 Oct 2026

Summary

Definition

History and exam

Key diagnostic factors

  • family history of pattern hair loss
  • gradual receding and thinning of frontal hairline, central scalp, and crown (vertex)
  • diffuse thinning of the central scalp with preservation of frontal and temporal hairline
Full details

Risk factors

  • family history of pattern hair loss
  • advancing age
  • polycystic ovary syndrome in women
  • metabolic syndrome
  • exogenous androgen intake
Full details

Diagnostic tests

1st tests to order

  • hair-pull test
Full details

Tests to consider

  • CBC with differential
  • thyroid function tests
  • serum ferritin
  • comprehensive metabolic panel
  • antinuclear antibodies
  • rapid plasma reagin
  • free testosterone
  • serum dehydroepiandrosterone (DHEA)-sulfate
  • sex hormone-binding globulin
  • androstenedione
  • 17-alpha hydroxyprogesterone
  • estradiol
  • LH
  • follicle-stimulating hormone (FSH)
  • dermatoscopy/trichoscopy
  • scalp biopsy
Full details

Treatment algorithm

ONGOING

men who opt for conservative management

men who opt for medical management

women who opt for conservative management

women who opt for medical management

unsatisfactory response to medical treatment

Contributors

Authors

Carolyn Goh, MD

Associate Clinical Professor

Department of Medicine

Division of Dermatology

UCLA Medical Center

Los Angeles, CA

Disclosures

CG has served as a consultant for Veradermics, Pfizer, AbbVie, and Arcutis. She has been on an advisory board for Veradermics and is on the speakers bureau for Pfizer and Sun Pharma. She is an investigator with CorEvitas.

Acknowledgements

Dr Carolyn Goh would like to gratefully acknowledge Dr Robert Haber, Dr Christiane Querfeld, and Dr Christopher R. Shea, previous contributors to this topic.

Disclosures

RH has an ownership interest in a company that manufactures light-based hair growth devices and receives royalties for the sales of a surgical device used in hair restoration surgery. CQ and CRS declare that they have no competing interests.

Peer reviewers

Jennifer Fu, MD

Director Hair Disorders Clinic

Department of Dermatology

University of California

San Francisco, CA

Disclosures

JF declares that she has consulted for Eli Lilly, Pfizer, and Sun Pharmaceuticals. She is an editor for DynaMed on related topics.

Peer reviewer acknowledgements

BMJ Best Practice topics are updated on a rolling basis in line with developments in evidence and guidance. The peer reviewers listed here have reviewed the content at least once during the history of the topic.

Disclosures

Peer reviewer affiliations and disclosures pertain to the time of the review.

References

Our in-house evidence and editorial teams collaborate with international expert contributors and peer reviewers to ensure that we provide access to the most clinically relevant information possible.

Key articles

European Dermatology Forum. S3 - European Dermatology Forum guideline for the treatment of androgenetic alopecia in women and in men. 2017 [internet publication].Full text

Carmina E, Azziz R, Bergfeld W, et al. Female pattern hair loss and androgen excess: a report from the multidisciplinary androgen excess and PCOS committee. J Clin Endocrinol Metab. 2019 Jul 1;104(7):2875-91. Abstract

Elhassan YS, Hawley JM, Cussen L, et al. Society for Endocrinology clinical practice guideline for the evaluation of androgen excess in women. Clin Endocrinol (Oxf). 2025 Oct;103(4):540-66.Full text  Abstract

Goodman NF, Bledsoe MB, Cobin RH, et al. American Association of Clinical Endocrinologists medical guidelines for the clinical practice for the diagnosis and treatment of hyperandrogenic disorders. Endocr Pract. 2001 Mar-Apr;7(2):120-34.Full text  Abstract

Reference articles

A full list of sources referenced in this topic is available to users with access to all of BMJ Best Practice.
  • Androgenetic alopecia images
  • Differentials

    • Diffuse alopecia areata
    • Acute telogen effluvium
    • Chronic telogen effluvium
    More Differentials
  • Guidelines

    • Society for Endocrinology clinical practice guideline for the evaluation of androgen excess in women
    • Female pattern hair loss and androgen excess: a report from the multidisciplinary Androgen Excess and PCOS Committee
    More Guidelines
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