Diverticular disease

References

Key articles

Hall J, Hardiman K, Lee S, et al. The American Society of Colon and Rectal Surgeons clinical practice guidelines for the treatment of left-sided colonic diverticulitis. Dis Colon Rectum. 2020 Jun;63(6):728-47.Full text  Abstract

Sartelli M, Weber DG, Kluger Y, et al. 2020 update of the WSES guidelines for the management of acute colonic diverticulitis in the emergency setting. World J Emerg Surg. 2020 May 7;15(1):32.Full text  Abstract

Stollman N, Smalley W, Hirano I; AGA Institute Clinical Guidelines Committee. American Gastroenterological Association Institute guideline on the management of acute diverticulitis. Gastroenterology. 2015 Dec;149(7):1944-9.Full text  Abstract

Peery AF, Shaukat A, Strate LL. AGA clinical practice update on medical management of colonic diverticulitis: expert review. Gastroenterology. 2021 Feb;160(3):906-11.e1.Full text  Abstract

American College of Radiology. ACR appropriateness criteria: left lower quadrant pain. 2023 [internet publication].Full text

Qaseem A, Etxeandia-Ikobaltzeta I, Lin JS, et al; Clinical Guidelines Committee of the American College of Physicians. Diagnosis and management of acute left-sided colonic diverticulitis: a clinical guideline from the American College of Physicians. Ann Intern Med. 2022 Mar;175(3):399-415.Full text  Abstract

Reference articles

1. National Institute for Health and Care Excellence (UK). Diverticular disease: diagnosis and management. Nov 2019 [internet publication].Full text

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3. Hall J, Hardiman K, Lee S, et al. The American Society of Colon and Rectal Surgeons clinical practice guidelines for the treatment of left-sided colonic diverticulitis. Dis Colon Rectum. 2020 Jun;63(6):728-47.Full text  Abstract

4. Tursi A. Diverticular disease: a therapeutic overview. World J Gastrointest Pharmacol Ther. 2010 Feb 6;1(1):27-35.Full text  Abstract

5. Andersen JC, Bundgaard L, Elbrønd H, et al. Danish national guidelines for treatment of diverticular disease. Dan Med J. 2012 May;59(5):C4453. Abstract

6. Hinchey EJ, Schaal PG, Richards GK. Treatment of perforated diverticular disease of the colon. Adv Surg. 1978;12:85-109. Abstract

7. Sartelli M, Weber DG, Kluger Y, et al. 2020 update of the WSES guidelines for the management of acute colonic diverticulitis in the emergency setting. World J Emerg Surg. 2020 May 7;15(1):32.Full text  Abstract

8. Kaiser AM, Jiang JK, Lake JP, et al. The management of complicated diverticulitis and the role of computed tomography. Am J Gastroenterol. 2005 Apr;100(4):910-7. Abstract

9. Imaeda H, Hibi T. The burden of diverticular disease and its complications: west versus east. Inflamm Intest Dis. 2018 Dec;3(2):61-8.Full text  Abstract

10. Lin OS, Soon MS, Wu SS, et al. Dietary habits and right-sided colonic diverticulosis. Dis Colon Rectum. 2000 Oct;43(10):1412-8. Abstract

11. Peery AF, Keku TO, Galanko JA, et al. Sex and race disparities in diverticulosis prevalence. Clin Gastroenterol Hepatol. 2020 Aug;18(9):1980-6.Full text  Abstract

12. Jacqueline D, Lince K, DeMario VK, et al. Diverticulitis in the under-40 population. Cureus. 2024 Mar;16(3):e56190.Full text  Abstract

13. Ray-Offor E, Egboh SM, Ijah RFOA, et al. Colonic diverticulosis at colonoscopy in Africa: a systematic review and meta-analysis of pooled estimates. Dig Surg. 2024;41(2):63-78. Abstract

14. Wijarnpreecha K, Ahuja W, Chesdachai S, et al. Obesity and the risk of colonic diverticulosis: a meta-analysis. Dis Colon Rectum. 2018 Apr;61(4):476-83. Abstract

15. Aune D, Sen A, Leitzmann MF, et al. Body mass index and physical activity and the risk of diverticular disease: a systematic review and meta-analysis of prospective studies. Eur J Nutr. 2017 Dec;56(8):2423-38.Full text  Abstract

16. Aune D, Sen A, Leitzmann MF, et al. Tobacco smoking and the risk of diverticular disease: a systematic review and meta-analysis of prospective studies. Colorectal Dis. 2017 Jul;19(7):621-33. Abstract

17. Wijarnpreecha K, Boonpheng B, Thongprayoon C, et al. Smoking and risk of colonic diverticulosis: a meta-analysis. J Postgrad Med. 2018 Jan-Mar;64(1):35-9.Full text  Abstract

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19. Shaikh A, Khrais A, Le A, et al. Pre-existing opioid use worsens outcomes in patients with diverticulitis. Cureus. 2023 Feb;15(2):e34624.Full text  Abstract

20. Strate LL, Morris AM. Epidemiology, pathophysiology, and treatment of diverticulitis. Gastroenterology. 2019 Apr;156(5):1282-98.e1.Full text  Abstract

21. Bode MK, Karttunen TJ, Makela J, et al. Type I and III collagens in human colon cancer and diverticulosis. Scand J Gastroenterol. 2000 Jul;35(7):747-52. Abstract

22. Bassotti G, Battaglia E, Spinozzi E, et al. Twenty-four hour recordings of colonic motility in patients with diverticular disease: evidence for abnormal motility and propulasive activity. Dis Colon Rectum. 2001 Dec;44(12):1814-20. Abstract

23. Leganger J, Søborg MK, Mortensen LQ, et al. Association between diverticular disease and Ehlers-Danlos syndrome: a 13-year nationwide population-based cohort study. Int J Colorectal Dis. 2016 Dec;31(12):1863-7. Abstract

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25. Schieffer KM, Kline BP, Yochum GS, et al. Pathophysiology of diverticular disease. Expert Rev Gastroenterol Hepatol. 2018 Jul;12(7):683-92. Abstract

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27. Simpson J, Scholefield JH, Spiller RC. Pathogenesis of colonic diverticula. Br J Surg 2002 May;89(5):546-54. Abstract

28. Tjiang E, Raja M, Hoyle C, et al. The role of nitric oxide in colonic compliance in diverticular disease. Gut. 1998 Jan;42 (suppl 1):A95.

29. Humphrey HN, Sibley P, Walker ET, et al. Genetic, epigenetic and environmental factors in diverticular disease: systematic review. BJS Open. 2024 May 8;8(3):zrae032.Full text  Abstract

30. Matrana MR, Margolin DA. Epidemiology and pathophysiology of diverticular disease. Clin Colon Rectal Surg. 2009 Aug;22(3):141-6.Full text  Abstract

31. Wess L, Eastwood MA, Wess TJ, et al. Cross linking of collagen is increased in colonic diverticulosis. Gut. 1995 Jul;37(1):91-4. Abstract

32. Aune D, Sen A, Norat T, et al. Dietary fibre intake and the risk of diverticular disease: a systematic review and meta-analysis of prospective studies. Eur J Nutr. 2020 Mar;59(2):421-32.Full text  Abstract

33. Dobbins C, Defontgalland D, Duthie G, et al. The relationship of obesity to the complications of diverticular disease. Colorectal Dis. 2006 Jan;8(1):37-40. Abstract

34. Strate LL, Liu YL, Aldoori WH, et al. Obesity increases the risks of diverticulitis and diverticular bleeding. Gastroenterology. 2009 Jan;136(1):115-22.Full text  Abstract

35. Sengupta N, Feuerstein JD, Jairath V, et al. Management of patients with acute lower gastrointestinal bleeding: an updated ACG guideline. Am J Gastroenterol. 2023 Feb 1;118(2):208-31.Full text  Abstract

36. Goh H, Bourne R. Non-steroidal anti-inflammatory drugs and perforated diverticular disease: a case-control study. Ann R Coll Surg Engl. 2002 Mar;84(2):93-6.Full text  Abstract

37. Stollman N, Smalley W, Hirano I; AGA Institute Clinical Guidelines Committee. American Gastroenterological Association Institute guideline on the management of acute diverticulitis. Gastroenterology. 2015 Dec;149(7):1944-9.Full text  Abstract

38. Sugihara Y, Kudo SE, Miyachi H, et al. Analysis of risk factors for colonic diverticular bleeding: a matched case-control study. Gut Liver. 2016 Mar;10(2):244-9.Full text  Abstract

39. Yuhara H, Corley DA, Nakahara F, et al. Aspirin and non-aspirin NSAIDs increase risk of colonic diverticular bleeding: a systematic review and meta-analysis. J Gastroenterol. 2014 Jun;49(6):992-1000. Abstract

40. Song JH, Kim YS, Lee JH, et al. Clinical characteristics of colonic diverticulosis in Korea: a prospective study. Korean J Intern Med. 2010 Jun;25(2):140-6.Full text  Abstract

41. Ma W, Nguyen LH, Song M, et al. Intake of dietary fiber, fruits, and vegetables and risk of diverticulitis. Am J Gastroenterol. 2019 Sep;114(9):1531-8.Full text  Abstract

42. Marlett JA, McBurney MI, Slavin JL; American Dietetic Association. Position of the American Dietetic Association: health implications of dietary fiber. J Am Diet Assoc. 2002 Jul;102(7):993-1000. Abstract

43. Peery AF, Shaukat A, Strate LL. AGA clinical practice update on medical management of colonic diverticulitis: expert review. Gastroenterology. 2021 Feb;160(3):906-11.e1.Full text  Abstract

44. American College of Radiology. ACR appropriateness criteria: left lower quadrant pain. 2023 [internet publication].Full text

45. Qaseem A, Etxeandia-Ikobaltzeta I, Lin JS, et al; Clinical Guidelines Committee of the American College of Physicians. Diagnosis and management of acute left-sided colonic diverticulitis: a clinical guideline from the American College of Physicians. Ann Intern Med. 2022 Mar;175(3):399-415.Full text  Abstract

46. Bonomo RA, Chow AW, Edwards MS, et al. 2024 clinical practice guideline update by the Infectious Diseases Society of America on complicated intra-abdominal infections: risk assessment, diagnostic imaging, and microbiological evaluation in adults, children, and pregnant people. Clin Infect Dis. 2024 Oct 4;79(supplement_3):S81-7.Full text  Abstract

47. Bonomo RA, Tamma PD, Abrahamian FM, et al. 2024 clinical practice guideline update by the Infectious Diseases Society of America on complicated intra-abdominal infections: diagnostic imaging of suspected acute diverticulitis in adults and pregnant people. Clin Infect Dis. 2024 Oct 4;79(supplement_3):S109-12.Full text  Abstract

48. Shin JH, Son BH, Kim H. Clinically distinguishing between appendicitis and right-sided colonic diverticulitis at initial presentation. Yonsei Med J. 2007 Jun 30;48(3):511-6.Full text  Abstract

49. Humes DJ. Diagnosing and managing acute diverticulitis. Practitioner. 2012 Jul-Aug;256(1753):21-3, 2-3. Abstract

50. Sharara AI, Ziade N, Shayto RH, et al. The natural history of incidental colonic diverticulosis on screening colonoscopy. Can J Gastroenterol Hepatol. 2018 Dec 6;2018:3690202.Full text  Abstract

51. Salzman H, Lillie D. Diverticular disease: diagnosis and treatment. Am Fam Physician. 2005 Oct 1;72(7):1229-34.Full text  Abstract

52. Jerjen F, Zaidi T, Chan S, et al. Magnetic resonance imaging for the diagnosis and management of acute colonic diverticulitis: a review of current and future use. J Med Radiat Sci. 2021 Sep;68(3):310-9.Full text  Abstract

53. Jensen DM, Machicado GA, Jutabha R, et al. Urgent colonoscopy for the diagnosis and treatment of severe diverticular hemorrhage. N Engl J Med. 2000 Jan 13;342(2):78-82.Full text  Abstract

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55. Kirsner JB. Historical origins of current IBD concepts. World J Gastroenterol. 2001 Apr;7(2):175-84. Abstract

56. Shepherd NA. Diverticular disease and chronic idiopathic inflammatory bowel disease: associations and masquerades. Gut. 1996 Jun;38(6):801-2. Abstract

57. Schmulson MJ, Drossman DA. What is new in Rome IV. J Neurogastroenterol Motil. 2017 Apr 30;23(2):151-63.Full text  Abstract

58. Hartge P, Hayes R, Reding D, et al. Complex ovarian cysts in postmenopausal women are not associated with ovarian cancer risk factors: preliminary data from the prostate, lung, colon, and ovarian cancer screening trial. Am J Obstet Gynecol. 2000 Nov;183(5):1232-7. Abstract

59. Qaseem A, Etxeandia-Ikobaltzeta I, Lin JS, et al; Clinical Guidelines Committee of the American College of Physicians. Colonoscopy for diagnostic evaluation and interventions to prevent recurrence after acute left-sided colonic diverticulitis: a clinical guideline from the American College of Physicians. Ann Intern Med. 2022 Mar;175(3):416-31.Full text  Abstract

60. Eberhardt F, Crichton M, Dahl C, et al. Role of dietary fibre in older adults with asymptomatic (AS) or symptomatic uncomplicated diverticular disease (SUDD): systematic review and meta-analysis. Maturitas. 2019 Dec;130:57-67. Abstract

61. Ünlü C, Daniels L, Vrouenraets BC, et al. A systematic review of high-fibre dietary therapy in diverticular disease. Int J Colorectal Dis. 2012 Apr;27(4):419-27.Full text  Abstract

62. van Dijk ST, Chabok A, Dijkgraaf MG, et al. Observational versus antibiotic treatment for uncomplicated diverticulitis: an individual-patient data meta-analysis. Br J Surg. 2020 Jul;107(8):1062-9.Full text  Abstract

63. Biondo S, Golda T, Kreisler E, et al. Outpatient versus hospitalization management for uncomplicated diverticulitis: a prospective, multicenter randomized clinical trial (DIVER trial). Ann Surg. 2014 Jan;259(1):38-44. Abstract

64. Sánchez-Velázquez P, Grande L, Pera M. Outpatient treatment of uncomplicated diverticulitis: a systematic review. Eur J Gastroenterol Hepatol. 2016 Jun;28(6):622-7. Abstract

65. Agency for Healthcare Research and Quality (AHRQ). Comparative effectiveness review no. 233: management of colonic diverticulitis. ​Rockville (MD): Agency for Healthcare Research and Quality (US); 2020.Full text

66. van Dijk ST, Bos K, de Boer MGJ, et al. A systematic review and meta-analysis of outpatient treatment for acute diverticulitis. Int J Colorectal Dis. 2018 May;33(5):505-12.Full text  Abstract

67. Alonso S, Pera M, Parés D, et al. Outpatient treatment of patients with uncomplicated acute diverticulitis. Colorectal Dis. 2010 Oct;12(10 online):e278-82. Abstract

68. Byrnes MC, Mazuski JE. Antimicrobial therapy for acute colonic diverticulitis. Surg Infect (Larchmt). 2009 Apr;10(2):143-54. Abstract

69. Mege D, Yeo H. Meta-analyses of current strategies to treat uncomplicated diverticulitis. Dis Colon Rectum. 2019 Mar;62(3):371-8. Abstract

70. Desai M, Fathallah J, Nutalapati V, et al. Antibiotics versus no antibiotics for acute uncomplicated diverticulitis: a systematic review and meta-analysis. Dis Colon Rectum. 2019 Aug;62(8):1005-12. Abstract

71. Emile SH, Elfeki H, Sakr A, et al. Management of acute uncomplicated diverticulitis without antibiotics: a systematic review, meta-analysis, and meta-regression of predictors of treatment failure. Tech Coloproctol. 2018 Jul;22(7):499-509. Abstract

72. Balk EM, Adam GP, Bhuma MR, et al. Diagnostic imaging and medical management of acute left-sided colonic diverticulitis: a systematic review. Ann Intern Med. 2022 Mar;175(3):379-87.Full text  Abstract

73. Araya-Quezada C, Torres-Bavestrello L, Gómez-Barbieri G, et al. Antibiotics for acute uncomplicated diverticulitis in hospitalized patients [in Spanish]. Medwave. 2021 Mar 26;21(2):e8140. Abstract

74. Garfinkle R, Salama E, Amar-Zifkin A, et al. Observational versus antibiotic therapy for acute uncomplicated diverticulitis: a non-inferiority meta-analysis based on a Delphi consensus. Surgery. 2022 Feb;171(2):328-35. Abstract

75. Dichman ML, Rosenstock SJ, Shabanzadeh DM. Antibiotics for uncomplicated diverticulitis. Cochrane Database Syst Rev. 2022 Jun 22;(6):CD009092.Full text  Abstract

76. Rusu A, Munteanu AC, Arbănași EM, et al. Overview of side-effects of antibacterial fluoroquinolones: new drugs versus old drugs, a step forward in the safety profile? Pharmaceutics. 2023 Mar 1;15(3):804.Full text  Abstract

77. Fugazzola P, Ceresoli M, Coccolini F, et al. The WSES/SICG/ACOI/SICUT/AcEMC/SIFIPAC guidelines for diagnosis and treatment of acute left colonic diverticulitis in the elderly. World J Emerg Surg. 2022 Jan 21;17(1):5.Full text  Abstract

78. Gregersen R, Mortensen LQ, Burcharth J, et al. Treatment of patients with acute colonic diverticulitis complicated by abscess formation: a systematic review. Int J Surg. 2016 Nov;35:201-8. Abstract

79. Toorenvliet BR, Swank H, Schoones JW, et al. Laparoscopic peritoneal lavage for perforated colonic diverticulitis: a systematic review. Colorectal Dis. 2010 Sep;12(9):862-7. Abstract

80. Angenete E, Bock D, Rosenberg J, et al. Laparoscopic lavage is superior to colon resection for perforated purulent diverticulitis - a meta-analysis. Int J Colorectal Dis. 2017 Feb;32(2):163-9.Full text  Abstract

81. Gehrman J, Angenete E, Björholt I, et al. Health economic analysis of laparoscopic lavage versus Hartmann's procedure for diverticulitis in the randomized DILALA trial. Br J Surg. 2016 Oct;103(11):1539-47.Full text  Abstract

82. Schultz JK, Wallon C, Blecic L, et al. One-year results of the SCANDIV randomized clinical trial of laparoscopic lavage versus primary resection for acute perforated diverticulitis. Br J Surg. 2017 Sep;104(10):1382-92. Abstract

83. Shaikh FM, Stewart PM, Walsh SR, et al. Laparoscopic peritoneal lavage or surgical resection for acute perforated sigmoid diverticulitis: a systematic review and meta-analysis. Int J Surg. 2017 Feb;38:130-7. Abstract

84. Galbraith N, Carter JV, Netz U, et al. Laparoscopic lavage in the management of perforated diverticulitis: a contemporary meta-analysis. J Gastrointest Surg. 2017 Sep;21(9):1491-9. Abstract

85. Abbas S. Resection and primary anastomosis in acute complicated diverticulitis, a systematic review of the literature. Int J Colorectal Dis. 2007 Apr;22(4):351-7. Abstract

86. Bezerra RP, Costa ACD, Santa-Cruz F, et al. Hartmann procedure or resection with primary anastomosis for treatment of perforated diverticulitis? Systematic review and meta-analysis. Arq Bras Cir Dig. 2021;33(3):e1546.Full text  Abstract

87. Horesh N, Emile SH, Khan SM, et al. Meta-analysis of randomized clinical trials on long-term outcomes of surgical treatment of perforated diverticulitis. Ann Surg. 2023 Nov 1;278(5):e966-72. Abstract

88. Lambrichts DP, Edomskis PP, van der Bogt RD, et al. Sigmoid resection with primary anastomosis versus the Hartmann's procedure for perforated diverticulitis with purulent or fecal peritonitis: a systematic review and meta-analysis. Int J Colorectal Dis. 2020 Aug;35(8):1371-86.Full text  Abstract

89. Ryan OK, Ryan ÉJ, Creavin B, et al. Systematic review and meta-analysis comparing primary resection and anastomosis versus Hartmann's procedure for the management of acute perforated diverticulitis with generalised peritonitis. Tech Coloproctol. 2020 Jun;24(6):527-43. Abstract

90. Janes S, Meagher A, Faragher IG, et al. The place of elective surgery following acute diverticulitis in young patients: when is surgery indicated? An analysis of the literature. Dis Colon Rectum. 2009 May;52(5):1008-16. Abstract

91. Yeow M, Syn N, Chong CS. Elective surgical versus conservative management of complicated diverticulitis: a systematic review and meta-analysis. J Dig Dis. 2022 Feb;23(2):91-8. Abstract

92. Longchamp G, Abbassi Z, Meyer J, et al. Surgical resection does not avoid the risk of diverticulitis recurrence - a systematic review of risk factors. Int J Colorectal Dis. 2021 Feb;36(2):227-37.Full text  Abstract

93. Siddiqui MR, Sajid MS, Qureshi S, et al. Elective laparoscopic sigmoid resection for diverticular disease has fewer complications than conventional surgery: a meta-analysis. Am J Surg. 2010 Jul;200(1):144-61. Abstract

94. Cirocchi RF, Farinella E, Trastulli S, et al. Elective sigmoid colectomy for diverticular disease. Laparoscopic vs open surgery: a systematic review. Colorectal Dis. 2012 Jun;14(6):671-83. Abstract

95. Andeweg CS, Berg R, Staal JB, et al. Patient-reported outcomes after conservative or surgical management of recurrent and chronic complaints of diverticulitis: systematic review and meta-analysis. Clin Gastroenterol Hepatol. 2016 Feb;14(2):183-90. Abstract

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99. Hupfeld L, Burcharth J, Pommergaard HC, et al. Risk factors for recurrence after acute colonic diverticulitis: a systematic review. Int J Colorectal Dis. 2017 May;32(5):611-22. Abstract

100. Kang G, Son S, Shin YM, et al. Recurrence of uncomplicated diverticulitis: a meta-analysis. Medicina (Kaunas). 2022 Jun 2;58(6):758.Full text  Abstract

101. Balk EM, Adam GP, Cao W, et al. Evaluation and management after acute left-sided colonic diverticulitis : a systematic review. Ann Intern Med. 2022 Mar;175(3):388-98.Full text  Abstract

102. Woods RJ, Lavery IC, Fazio VW, et al. Internal fistulas in diverticular disease. Dis Clon Rectum. 1988 Aug;31(8):591-6. Abstract

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105. Koo CH, Chang JHE, Syn NL, et al. Systematic review and meta-analysis on colorectal cancer findings on colonic evaluation after CT-confirmed acute diverticulitis. Dis Colon Rectum. 2020 May;63(5):701-9. Abstract

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