Last reviewed: June 2020
Last updated: April  2020

Summary

Definition

History and exam

Key diagnostic factors

  • parotitis
  • history of missed or no vaccination or possible vaccine failure (primary or secondary)

Other diagnostic factors

  • constitutional symptoms
  • orchitis
  • oophoritis
  • aseptic meningitis
  • mastitis
  • encephalitis
  • deafness

Risk factors

  • unvaccinated status
  • immunosuppression
  • healthcare worker
  • international traveler
  • close-contact living (college students, prisoners, military)
  • vaccine failure

Diagnostic investigations

Investigations to consider

  • CBC and differential
  • lumbar puncture
  • serum mumps IgM
  • serum mumps IgG
  • reverse transcriptase PCR
  • serum amylase
  • viral culture (CSF, saliva, or urine)
  • CT head
More investigations to consider

Treatment algorithm

Contributors

Consultant in Community Child Health

Great Ormond Street Hospital

London

UK

Disclosures

DE is involved in expert legal work where those with parental responsibility disagree as to whether a child should be immunised.

Professor of Children's Health

UCL Institute of Child Health

London

UK

Disclosures

HB declares that she has no competing interests.

Dr David Elliman and Professor Helen Bedford would like to gratefully acknowledge Dr Kristin Furfari, a previous contributor to this topic. KF declares that she has no competing interests.

Peer reviewersVIEW ALL

Assistant Professor of Clinical Dermatology

Columbia University

New York

NY

Disclosures

RU declares that he has no competing interests.

Assistant Professor of Medicine

Division of Infectious Diseases

University of Vermont College of Medicine

Burlington

VT

Disclosures

CDH declares that he has no competing interests.

Deputy Director

National Centre for Immunisation Research and Surveillance

Postgraduate Fellow

Department Of Microbiology and Infectious Diseases

The Children’s Hospital

Westmead

New South Wales

Australia

Disclosures

KM declares that she has no competing interests.

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