The incidence of ALS in Europe and the US is about 1.5 to 2.5 per 100,000 per year, with a prevalence of 2.7 to 7.4 per 100,000. The mean age of onset is about 57 years. In age groups <70 years of age, the male-to-female ratio is 1.3:1.5. For age groups >70 years of age, the ratio is close to 1. There are no definite data regarding the distribution of disease among different races, although a higher incidence of ALS in white people as compared with Asian, African, and Hispanic groups has been suggested.
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