Nearly half of Ebola virus disease survivors in one study from Sierra Leone reported difficulty concentrating at follow-up visits. This may apply to Marburg virus disease survivors as well.
Has been reported in severe disease. May be caused by dehydration initially, but may be a consequence of disseminated intravascular coagulation or direct damage to the kidneys by Marburg virus in later stages. Early recognition by monitoring urine output and blood biochemistry enables prompt action to be taken.
14% to 60% of Ebola virus disease survivors reported ocular symptoms including eye pain, clear discharge, red eyes, and blurred vision, or were found to have uveitis at follow-up visits. This has been found in Marburg virus disease survivors as well. The central nervous system and globe are thought to be filovirus sanctuary sites where disease can be persistent.
Headache, confusion, seizures, memory loss, headaches, cranial nerve abnormalities, and tremor may occur, and neurological symptoms have been documented in both acute illness and among Ebola virus survivors. The central nervous system and globe are thought to be filovirus sanctuary sites where disease can be persistent.
Psychological distress was common among Ebola virus disease survivors in the 2014 to 2016 West Africa Ebola virus disease outbreak. Exposure to death in the treatment units and stigma in the community induced post-traumatic stress reactions and symptoms of depression. These symptoms are also common among Marburg virus disease survivors, and would be expected to be especially prevalent in outbreak settings.
Asthenia has been reported among Marburg disease survivors.
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