Approach

Zinc deficiency can present in many ways and should be considered in people with at-risk conditions. Aside from the severe rash of acrodermatitis enteropathica seen in profound zinc deficiency, the manifestations of zinc deficiency are protean and non-specific. The diagnosis can be especially elusive because symptoms may overlap with the many conditions that predispose to zinc deficiency. For this reason, a high index of suspicion is critical.com.bmj.content.model.Caption@216dfa2a[Figure caption and citation for the preceding image starts]: Acrodermatitis enteropathica on the face seen with severe zinc deficiencyAdapted from Maverakis E, Lynch PJ, Fazel N. Acrodermatitis enteropathica. Dermatol Online J. 2007;13:11; used with permission [Citation ends].com.bmj.content.model.Caption@39a671dd[Figure caption and citation for the preceding image starts]: Acrodermatitis enteropathica seen with severe zinc deficiencyAdapted from Maverakis E, Lynch PJ, Fazel N. Acrodermatitis enteropathica. Dermatol Online J. 2007;13:11; used with permission [Citation ends].

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