为什么需要循证医学?

  • Emparanza JI, Cabello JB and Burls AJE. Does evidence-based practice improve patient outcomes? An analysis of a natural experiment in a Spanish hospital. J Eval Clin Pract 2015;21:1059-1065. https://ncbi.nlm.nih.gov/pubmed/26516021/
  • Kiessling A, Lewitt M, Henriksson P, et al. Case-based training of evidence-based clinical practice in primary care and decreased mortality in patients with coronary heart disease. Ann Fam Med 2011;9:211–218. https://www.ncbi.nlm.nih.gov/pubmed/21555748
  • Shuval K, Linn S, Brevis M, et al. Association between primary care physicians' evidence-based medicine knowledge and quality of care. Int J Qual Health Care 2010;22:16–23. https://www.ncbi.nlm.nih.gov/pubmed/19951965
  • Barratt A. Evidence based medicine and shared decision making: the challenge of getting both evidence and preferences into health care. Patient Educ Couns 2008;73:407–412. https://www.ncbi.nlm.nih.gov/pubmed/18845414
  • Lockwood D, Armstrong M, Grant A. Integrating evidence based medicine into routine clinical practice: seven years' experience at the Hospital for Tropical Diseases, London. BMJ 2004;329:1020–1023. https://www.ncbi.nlm.nih.gov/pubmed/15514349
  • Lucas BP, Evans AT, Reilly BM, et al. The impact of evidence on physicians' inpatient treatment decisions. J Gen Intern Med 2004;19:402–409. https://www.ncbi.nlm.nih.gov/pubmed/15109337
  • Rosenberg W, Donald A. Evidence based medicine: an approach to clinical problem-solving. BMJ 1995;310:1122–1126. https://www.ncbi.nlm.nih.gov/pubmed/7742682

什么是循证医学?

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临床问题、检索与研究选择

  • Ioannidis, J. The need to consider the wider agenda in systematic reviews and meta-analyses: breadth, timing, and depth of the evidence. BMJ 2010;341:c4875 https://www.bmj.com/content/341/bmj.c4875
  • Glanville J, Bayliss S, Booth A, et al. So many filters, so little time: the development of a search filter appraisal checklist. J Med Libr Assoc 2008; 96(4):356–361. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2568852/
  • Thomas J, Kneale D, McKenzie JE, et al.  Chapter 2: Determining the scope of the review and the questions it will address. In: Higgins JPT, Thomas J, Chandler J, Cumpston M, Li T, Page MJ, Welch VA (editors). Cochrane Handbook for Systematic Reviews of Interventions version 6.3 (updated February 2022). Cochrane, 2022. Available from www.training.cochrane.org/handbook.
  • Lefebvre C, Glanville J, Briscoe S, et al. Chapter 4: Searching for and selecting studies. In: Higgins JPT, Thomas J, Chandler J, Cumpston M, Li T, Page MJ, Welch VA (editors). Cochrane Handbook for Systematic Reviews of Interventions version 6.3 (updated February 2022). Cochrane, 2022. Available from www.training.cochrane.org/handbook.
  • Li T, Higgins JPT and Deeks JJ. Chapter 5: Collecting data. In: Higgins JPT, Thomas J, Chandler J, Cumpston M, Li T, Page MJ, Welch VA (editors). Cochrane Handbook for Systematic Reviews of Interventions version 6.3 (updated February 2022). Cochrane, 2022. Available from www.training.cochrane.org/handbook.
  • Lefebvre C, Glanville J, Wieland LS, et al. Methodological developments in searching for studies for systematic reviews: past, present and future? Systematic Reviews 2013;2:78. https://www.ncbi.nlm.nih.gov/pubmed/24066664

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严格评价的技巧

  • Boutron I, Page MJ, Higgins JPT, et al. Chapter 7: Considering bias and conflicts of interest among the included studies. In: Higgins JPT, Thomas J, Chandler J, Cumpston M, Li T, Page MJ, Welch VA (editors). Cochrane Handbook for Systematic Reviews of Interventions version 6.3 (updated February 2022). Cochrane, 2022. Available from www.training.cochrane.org/handbook
  • Higgins JPT, Savović J, Page MJ, et al. Chapter 8: Assessing risk of bias in a randomized trial.  In: Higgins JPT, Thomas J, Chandler J, Cumpston M, Li T, Page MJ, Welch VA (editors). Cochrane Handbook for Systematic Reviews of Interventions version 6.3 (updated February 2022). Cochrane, 2022. Available from www.training.cochrane.org/handbook
  • Page MJ, Higgins JPT and Sterne JAC. Chapter 13: Assessing risk of bias due to missing results in a synthesis.  In: Higgins JPT, Thomas J, Chandler J, Cumpston M, Li T, Page MJ, Welch VA (editors). Cochrane Handbook for Systematic Reviews of Interventions version 6.3 (updated February 2022). Cochrane, 2022. Available from www.training.cochrane.org/handbook
  • Sterne JAC, Hernán MA, McAleenan A, et al. Chapter 25: Assessing risk of bias in a non-randomized study. In: Higgins JPT, Thomas J, Chandler J, Cumpston M, Li T, Page MJ, Welch VA (editors). Cochrane Handbook for Systematic Reviews of Interventions version 6.3 (updated February 2022). Cochrane, 2022. Available from www.training.cochrane.org/handbook
  • Sedgwick P. Bias in experimental study designs: randomised controlled trials with parallel groups. BMJ 2015;351. https://www.bmj.com/content/351/bmj.h3869
  • Windish D. Searching for the right evidence: how to answer your clinical questions using the 6S hierarchy. Evidence-Based Medicine 2013;18:93-97. https://www.ncbi.nlm.nih.gov/pubmed/23048189
  • Guyatt GH, Oxman AD, Kunz R, et al. What is "quality of evidence" and why is it important to clinicians? BMJ 2008;336:995–998. https://www.ncbi.nlm.nih.gov/pubmed/18456631
  • Haynes RB. Of studies, syntheses, synopses, summaries, and systems: the "5S" evolution of information services for evidence-based healthcare decisions. Evid Based Med 2006;11:162–164. https://www.ncbi.nlm.nih.gov/pubmed/17213159
  • Barton S. Which clinical studies provide the best evidence? BMJ 2000;321(7256):255–256. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1118259/
  • Greenhalgh T. How to read a paper. Assessing the methodological quality of published papers. BMJ 1997;315:305–308. https://www.ncbi.nlm.nih.gov/pubmed/9274555
  • Greenhalgh T. How to read a paper. Getting your bearings (deciding what the paper is about). BMJ 1997;315:243–246. https://www.ncbi.nlm.nih.gov/pubmed/9253275
  • Jaeschke R, Guyatt G, Sackett DL. Users' guides to the medical literature. III. How to use an article about a diagnostic test. A. Are the results of the study valid? Evidence-Based Medicine Working Group. JAMA 1994;271:389-391. https://www.hopkinsmedicine.org/gim/_pdf/JAMA/3A-Diagnostic_Test.pdf
  • Jaeschke R, Guyatt GH, Sackett DL. Users' guides to the medical literature. III. How to use an article about a diagnostic test. B. What are the results and will they help me in caring for my patients? The Evidence-Based Medicine Working Group. JAMA 1994;271:703-707. https://www.hopkinsmedicine.org/gim/_pdf/JAMA/3B-Diagnostic_Test.pdf

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了解统计学

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了解Meta分析

GRADE分级

循证医学实践与共享决策

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