EBM概念介绍:重要资源目录
为什么需要循证医学?
- Emparanza JI, Cabello JB and Burls AJE. Does evidence-based practice improve patient outcomes? An analysis of a natural experiment in a Spanish hospital. J Eval Clin Pract 2015;21:1059-1065. https://ncbi.nlm.nih.gov/pubmed/26516021/
- Kiessling A, Lewitt M, Henriksson P, et al. Case-based training of evidence-based clinical practice in primary care and decreased mortality in patients with coronary heart disease. Ann Fam Med 2011;9:211–218. https://www.ncbi.nlm.nih.gov/pubmed/21555748
- Shuval K, Linn S, Brevis M, et al. Association between primary care physicians' evidence-based medicine knowledge and quality of care. Int J Qual Health Care 2010;22:16–23. https://www.ncbi.nlm.nih.gov/pubmed/19951965
- Barratt A. Evidence based medicine and shared decision making: the challenge of getting both evidence and preferences into health care. Patient Educ Couns 2008;73:407–412. https://www.ncbi.nlm.nih.gov/pubmed/18845414
- Lockwood D, Armstrong M, Grant A. Integrating evidence based medicine into routine clinical practice: seven years' experience at the Hospital for Tropical Diseases, London. BMJ 2004;329:1020–1023. https://www.ncbi.nlm.nih.gov/pubmed/15514349
- Lucas BP, Evans AT, Reilly BM, et al. The impact of evidence on physicians' inpatient treatment decisions. J Gen Intern Med 2004;19:402–409. https://www.ncbi.nlm.nih.gov/pubmed/15109337
- Rosenberg W, Donald A. Evidence based medicine: an approach to clinical problem-solving. BMJ 1995;310:1122–1126. https://www.ncbi.nlm.nih.gov/pubmed/7742682
什么是循证医学?
- Greenhalgh T. Evidence based medicine: a movement in crisis? BMJ 2014;348:g3725 https://www.ncbi.nlm.nih.gov/pubmed/24927763
- Glasziou P, What is EBM? Evidence-Based Medicine 2011;16:129-130. https://www.ncbi.nlm.nih.gov/pubmed/21949274
- Dickersin K. Evidence based medicine: increasing, not dictating, choice. BMJ 2007;334:s10 https://www.bmj.com/content/334/suppl_1/s10
- Reilly BM. The essence of EBM. BMJ 2004;329;991–992. https://www.ncbi.nlm.nih.gov/pubmed/15514321
- Sackett DL, Rosenberg W, Gray JA, et al. Evidence-based medicine: what it is and what it isn’t. BMJ 1996;312:71–72. https://www.ncbi.nlm.nih.gov/pubmed/8555924
- Evidence-Based Medicine Working Group. Evidence-based medicine. A new approach to teaching the practice of medicine. JAMA 1992;268;2420–2425. https://www.ncbi.nlm.nih.gov/pubmed/1404801
网站:
- The history of evidence based medicine - Oral History project from JAMA and The BMJ. Available from https://www.bmj.com/campaign/ebm-history
临床问题、检索与研究选择
- Ioannidis, J. The need to consider the wider agenda in systematic reviews and meta-analyses: breadth, timing, and depth of the evidence. BMJ 2010;341:c4875 https://www.bmj.com/content/341/bmj.c4875
- Glanville J, Bayliss S, Booth A, et al. So many filters, so little time: the development of a search filter appraisal checklist. J Med Libr Assoc 2008; 96(4):356–361. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2568852/
- Thomas J, Kneale D, McKenzie JE, et al. Chapter 2: Determining the scope of the review and the questions it will address. In: Higgins JPT, Thomas J, Chandler J, Cumpston M, Li T, Page MJ, Welch VA (editors). Cochrane Handbook for Systematic Reviews of Interventions version 6.3 (updated February 2022). Cochrane, 2022. Available from www.training.cochrane.org/handbook.
- Lefebvre C, Glanville J, Briscoe S, et al. Chapter 4: Searching for and selecting studies. In: Higgins JPT, Thomas J, Chandler J, Cumpston M, Li T, Page MJ, Welch VA (editors). Cochrane Handbook for Systematic Reviews of Interventions version 6.3 (updated February 2022). Cochrane, 2022. Available from www.training.cochrane.org/handbook.
- Li T, Higgins JPT and Deeks JJ. Chapter 5: Collecting data. In: Higgins JPT, Thomas J, Chandler J, Cumpston M, Li T, Page MJ, Welch VA (editors). Cochrane Handbook for Systematic Reviews of Interventions version 6.3 (updated February 2022). Cochrane, 2022. Available from www.training.cochrane.org/handbook.
- Lefebvre C, Glanville J, Wieland LS, et al. Methodological developments in searching for studies for systematic reviews: past, present and future? Systematic Reviews 2013;2:78. https://www.ncbi.nlm.nih.gov/pubmed/24066664
网站:
- Centre for Evidence-Based Medicine. Asking Focused Questions. Available from https://www.cebm.ox.ac.uk/resources/ebm-tools/asking-focused-questions
- Centre for Evidence-Based Medicine. Finding the Evidence 1 – Using PICO to formulate a search question. Available from https://www.cebm.ox.ac.uk/resources/ebm-tools//finding-the-evidence-1-using-pico-to-formulate-a-search-question
- The InterTASC Information Specialists' Sub-Group (ISSG) Search Filters Resource: Available from https://sites.google.com/a/york.ac.uk/issg-search-filters-resource/
- U.S. National Library of Medicine. PubMed Special Queries. Available from https://www.nlm.nih.gov/bsd/special_queries.html
严格评价的技巧
- Boutron I, Page MJ, Higgins JPT, et al. Chapter 7: Considering bias and conflicts of interest among the included studies. In: Higgins JPT, Thomas J, Chandler J, Cumpston M, Li T, Page MJ, Welch VA (editors). Cochrane Handbook for Systematic Reviews of Interventions version 6.3 (updated February 2022). Cochrane, 2022. Available from www.training.cochrane.org/handbook
- Higgins JPT, Savović J, Page MJ, et al. Chapter 8: Assessing risk of bias in a randomized trial. In: Higgins JPT, Thomas J, Chandler J, Cumpston M, Li T, Page MJ, Welch VA (editors). Cochrane Handbook for Systematic Reviews of Interventions version 6.3 (updated February 2022). Cochrane, 2022. Available from www.training.cochrane.org/handbook
- Page MJ, Higgins JPT and Sterne JAC. Chapter 13: Assessing risk of bias due to missing results in a synthesis. In: Higgins JPT, Thomas J, Chandler J, Cumpston M, Li T, Page MJ, Welch VA (editors). Cochrane Handbook for Systematic Reviews of Interventions version 6.3 (updated February 2022). Cochrane, 2022. Available from www.training.cochrane.org/handbook
- Sterne JAC, Hernán MA, McAleenan A, et al. Chapter 25: Assessing risk of bias in a non-randomized study. In: Higgins JPT, Thomas J, Chandler J, Cumpston M, Li T, Page MJ, Welch VA (editors). Cochrane Handbook for Systematic Reviews of Interventions version 6.3 (updated February 2022). Cochrane, 2022. Available from www.training.cochrane.org/handbook
- Sedgwick P. Bias in experimental study designs: randomised controlled trials with parallel groups. BMJ 2015;351. https://www.bmj.com/content/351/bmj.h3869
- Windish D. Searching for the right evidence: how to answer your clinical questions using the 6S hierarchy. Evidence-Based Medicine 2013;18:93-97. https://www.ncbi.nlm.nih.gov/pubmed/23048189
- Guyatt GH, Oxman AD, Kunz R, et al. What is "quality of evidence" and why is it important to clinicians? BMJ 2008;336:995–998. https://www.ncbi.nlm.nih.gov/pubmed/18456631
- Haynes RB. Of studies, syntheses, synopses, summaries, and systems: the "5S" evolution of information services for evidence-based healthcare decisions. Evid Based Med 2006;11:162–164. https://www.ncbi.nlm.nih.gov/pubmed/17213159
- Barton S. Which clinical studies provide the best evidence? BMJ 2000;321(7256):255–256. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1118259/
- Greenhalgh T. How to read a paper. Assessing the methodological quality of published papers. BMJ 1997;315:305–308. https://www.ncbi.nlm.nih.gov/pubmed/9274555
- Greenhalgh T. How to read a paper. Getting your bearings (deciding what the paper is about). BMJ 1997;315:243–246. https://www.ncbi.nlm.nih.gov/pubmed/9253275
- Jaeschke R, Guyatt G, Sackett DL. Users' guides to the medical literature. III. How to use an article about a diagnostic test. A. Are the results of the study valid? Evidence-Based Medicine Working Group. JAMA 1994;271:389-391. https://www.hopkinsmedicine.org/gim/_pdf/JAMA/3A-Diagnostic_Test.pdf
- Jaeschke R, Guyatt GH, Sackett DL. Users' guides to the medical literature. III. How to use an article about a diagnostic test. B. What are the results and will they help me in caring for my patients? The Evidence-Based Medicine Working Group. JAMA 1994;271:703-707. https://www.hopkinsmedicine.org/gim/_pdf/JAMA/3B-Diagnostic_Test.pdf
网站:
- Catalogue of Bias. Available from https://catalogofbias.org/
- Centre for Evidence-Based Medicine. Critical Appraisal tools. Available from https://www.cebm.net/2014/06/critical-appraisal/
- Consolidated Standards of Reporting Trials. CONSORT Statement and Extensions. Available from http://www.consort-statement.org/
- Critical Appraisal Skills Programme. CASP checklists. Available from https://www.casp-uk.net/casp-tools-checklists
- Preferred Reporting Items for Systematic Reviews and Meta-Analyses. PRISMA Statement. Available from https://www.prisma-statement.org/PRISMAStatement/Default.aspx
- Scottish Intercollegiate Guidelines Network. Critical Appraisal: Notes and checklists. Available from https://www.sign.ac.uk/methodology/checklists.html
了解统计学
- Sedgwick P. What is significance? BMJ 2015;350:h3475 https://www.bmj.com/content/350/bmj.h3475
- Sedgwick P. What are the risks? BMJ 2015;350:h2931 https://www.bmj.com/content/350/bmj.h2931
- Sedgwick P. Clinical significance versus statistical significance. BMJ 2014;348:g2130 https://www.bmj.com/content/348/bmj.g2130
- Understanding statistical terms: 5. Systematic reviews and meta-analysis. Drug Ther Bull 2009;47:95–96. https://www.ncbi.nlm.nih.gov/pubmed/19654420
- Understanding statistical terms: 4. Diagnostic tests. Drug Ther Bull 2009;47:71–72. https://www.ncbi.nlm.nih.gov/pubmed/19494344
- Understanding statistical terms: 3. Topics to do with study design. Drug Ther Bull 2009;47:59–60. https://www.ncbi.nlm.nih.gov/pubmed/19423679
- Understanding statistical terms: 2. Drug Ther Bull 2009;47:35–36. https://www.ncbi.nlm.nih.gov/pubmed/19261839
- Understanding statistical terms: 1. Drug Ther Bull 2009;47:22–24. https://www.ncbi.nlm.nih.gov/pubmed/19193703
- Hatala R, Keitz S, Wyer P, et al. Tips for learners of evidence-based medicine: 4. Assessing heterogeneity of primary studies in systematic reviews and whether to combine their results. CMAJ 2005;172:661–665. https://www.ncbi.nlm.nih.gov/pubmed/15738493
- Barratt A, WYer PC, Hatala R, et al. Tips for learners of evidence-based medicine: 1. Relative risk reduction, absolute risk reduction and number needed to treat. CMAJ 2004;171:353–358. https://www.ncbi.nlm.nih.gov/pubmed/15313996
- Montori VM, Kleinbart J, Newman TB, et al. Tips for learners of evidence-based medicine: 2. Measures of precision (confidence intervals). CMAJ 2004;171:611–615. https://www.ncbi.nlm.nih.gov/pubmed/15367466
- Greenhalgh T. How to read a paper. Statistics for the non-statistician II: significant relationships and their pitfalls. BMJ 1997;315:422–425. https://www.ncbi.nlm.nih.gov/pubmed/9277611
- Greenhalgh T. How to read a paper. Statistics for the non-statistician I: different types of data need different statistical tests. BMJ 1997;315:364–366. https://www.ncbi.nlm.nih.gov/pubmed/927046
网站:
- BMJ Learning Understanding statistics 1: presenting data from clinical trials An interactive module which outlines the basics of different ways of presenting statistical data from a clinical trial.
- BMJ Learning Understanding statistics 2: is there a significant difference? An interactive module which uses practical examples to work through to help you learn how to interpret the results of a trial, including what statistical significance means.
- BMJ Statistics Notes Co-written by Martin Bland and Doug Altman (with some exceptions) these notes cover everything from basic to more advanced medical statistics with practical examples. A complete list of BMJ Statistics Notes is available at https://www-users.york.ac.uk/~mb55/pubs/pbstnote.htm
了解Meta分析
- Perera R, Heneghan C. Interpreting meta-analysis in systematic reviews. Evid Based Med 2008;13:67–69. https://www.ncbi.nlm.nih.gov/pubmed/18515615
- Greenhalgh T. How to read a paper. Papers that summarise other papers (systematic reviews and meta-analyses). BMJ 1997;315:672–675. https://www.ncbi.nlm.nih.gov/pubmed/9310574
GRADE分级
- GRADE Series. Journal of Clinical Epidemiology. https://www.jclinepi.com/content/jce-GRADE-Series
循证医学实践与共享决策
- Daly RL, Bunn F and Goodman C. Shared decision-making for people living with dementia in extended care settings: a systematic review. BMJ Open 2018;8:e018977. https://bmjopen.bmj.com/content/8/6/e018977
- Walsh, K. Online clinical decision support: how it is used at the point-of-care. BMJ Simulation and Technology Enhanced Learning 2017; 0: 1-2 https://stel.bmj.com/content/early/2017/01/05/bmjstel-2016-000170.info
- McCartney M, Treadwell J, Maskrey N, et al. Making evidence based medicine work for individual patients. BMJ 2016; 353. https://www.bmj.com/content/353/bmj.i2452
- Agoritsas T, Heen AF, Brandt L, et al. Decision aids that really promote shared decision making: the pace quickens. BMJ 2015;350. https://www.ncbi.nlm.nih.gov/pubmed/25670178
- Stiggelbout AM, Van der Weijden T, De Wit MPT, et al. Shared decision making: really putting patients at the centre of healthcare. BMJ 2012;344 https://www.ncbi.nlm.nih.gov/pubmed/22286508
- Kitson A, Straus SE. The knowledge-to-action cycle: identifying the gaps. CMAJ 2010;182:E73–E77. https://www.ncbi.nlm.nih.gov/pubmed/19948812
- Whitely R. Cultural competence, evidence-based medicine, and evidence-based practices. Psychiatr Serv 2007;58:1588–1590. https://www.ncbi.nlm.nih.gov/pubmed/18048561
- Hasnain-Wynia R. Is evidence-based medicine patient-centered and is patient-centered care evidence-based? Health Serv Res 2006;41:1–8. https://www.ncbi.nlm.nih.gov/pubmed/16479681
- Guyatt G, Cook D, Haynes B. Evidence based medicine has come a long way. BMJ 2004;329;990–991. https://www.ncbi.nlm.nih.gov/pubmed/15514320
- Kotaska A. Inappropriate use of randomised trials to evaluate complex phenomena: case study of vaginal breech delivery. BMJ 2004;329:1039–1042. https://www.ncbi.nlm.nih.gov/pubmed/15514356
- Lockwood S. "Evidence of me" in evidence based medicine? BMJ 2004;329;1033–1035. https://www.ncbi.nlm.nih.gov/pubmed/15514354
- Slowther A, Ford S, Schofield T. Ethics of evidence based medicine in the primary care setting. J Med Ethics 2004;30:151–155. https://www.ncbi.nlm.nih.gov/pubmed/15082808
- White B. Making evidence-based medicine doable in everyday practice. Fam Pract Manag 2004;11:51–58. https://www.ncbi.nlm.nih.gov/pubmed/15011482
- Schattner A, Fletcher RH. Research evidence and the individual patient. QJM 2003;96:1–5. https://www.ncbi.nlm.nih.gov/pubmed/12509644
网站
- BMJ Rapid Recommendations. Available from https://www.bmj.com/rapid-recommendations
- Cochrane Knowledge Translation. Available from https://community.cochrane.org/review-production/knowledge-translation
- Knowledge Translation Unit. Available from https://knowledgetranslation.co.za/
- National Institute for Health and Care Excellence (NICE) Shared decision making and patient decision aids. Available from https://www.nice.org.uk/about/what-we-do/our-programmes/nice-guidance/nice-guidelines/shared-decision-making