Last reviewed: November 2017
Last updated: October  2016

Summary

Definition

History and exam

Key diagnostic factors

  • exposure to rodent excreta
  • dyspnea
  • hypotension

Other diagnostic factors

  • fever
  • myalgias
  • GI symptoms
  • headache
  • normal or low oxygen saturation
  • lung rales

Risk factors

  • exposure to rodent excreta
  • close contact with hantavirus-infected humans
  • male gender
  • white race

Diagnostic investigations

1st investigations to order

  • CBC
  • CXR
  • IgM and IgG serologies for hantavirus
  • reverse transcriptase PCR (RT-PCR)
Full details

Investigations to consider

  • ABG
  • serum lactate
  • ECG
  • echocardiogram
  • flow-directed pulmonary artery catheter (Swan-Ganz catheter)
  • lung biopsy
Full details

Emerging tests

  • serum viral-RNA load
  • neutralizing antibody
Full details

Treatment algorithm

Contributors

Authors VIEW ALL

Michael Sands

Professor of Medicine

College of Medicine

University of Florida

Jacksonville

FL

Disclosures

MS declares that he has no competing interests.

Carmen Isache

Assistant Professor of Medicine

College of Medicine

University of Florida

Jacksonville

FL

Disclosures

CI declares that she has no competing interests.

Peer reviewers VIEW ALL

Professor

School of Public Health and Primary Care

The Chinese University of Hong Kong

Prince of Wales Hospital

Shatin

Hong Kong

Disclosures

TWW declares that he has no competing interests.

Medical Epidemiologist

Parasitic Diseases Branch

CDC/NCZVED/DPD

Atlanta

GA

Disclosures

EF declares that she has no competing interests.

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