Last reviewed: November 2017
Last updated: July  2016

Summary

Definition

History and exam

Key diagnostic factors

  • history of soil exposure in endemic area
  • infection with other parasites

Other diagnostic factors

  • abdominal pain
  • altered bowel habit
  • weight loss
  • fever (hyperinfection)
  • signs of sepsis (hyperinfection)
  • chronic cough
  • wheezing
  • pruritus or dermatitis
  • larva currens
  • urticaria
  • cutaneous larvae migrans
  • apparent drug reaction rash (hyperinfection)
  • other skin complaints
  • symptoms and signs of inflammatory bowel disease

Risk factors

  • soil exposure in or migrants from an endemic area of the world
  • international travelers
  • corticosteroids (risk of hyperinfection)
  • HTLV-1 infection (risk of hyperinfection)
  • impaired immunity

Diagnostic investigations

1st investigations to order

  • stool ova and parasites (O & P) examination
  • CBC with differential
  • therapeutic trial with ivermectin (in specific situations)
Full details

Investigations to consider

  • sputum O & P examination
  • clinical sample (nonstool or sputum) O & P examination
  • strongyloides IgG serology
  • tissue biopsy
Full details

Treatment algorithm

Contributors

Authors VIEW ALL

David R. Boulware

Lois & Richard King Distinguished Associate Professor

Associate Director of Global Health

Department of Medicine

University of Minnesota

Minneapolis

MN

Disclosures

DRB is an author of a number of references cited in this monograph.

Peer reviewers VIEW ALL

Assistant Professor

Department of Pediatrics

Boston Medical Center

Boston University

Boston

MA

Disclosures

EB declares that she is on a speaker's bureau for Merck. She is an author of a reference cited in this monograph.

Associate Professor of Pediatrics

West Virginia University School of Medicine

Morgantown

WV

Disclosures

LN is an author of a reference cited in this monograph.

Professor of International Medicine and Honorary Consultant Physician

Liverpool School of Tropical Medicine

Liverpool

UK

Disclosures

GG declares he has no competing interests.

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