Last reviewed: November 2017
Last updated: October  2016

Summary

Definition

History and exam

Key diagnostic factors

  • neck pain
  • tender, firm, enlarged thyroid
  • fever
  • palpitations

Other diagnostic factors

  • recent viral infection
  • myalgia
  • malaise
  • tremor
  • heat intolerance

Risk factors

  • viral infection
  • HLA-Bw35 and B35

Diagnostic investigations

1st investigations to order

  • TSH
  • total T4, total T3, T3 resin uptake, free thyroxine index
  • T3:T4 ratio
  • radioactive iodine uptake
  • ESR
  • CRP
  • antithyroid antibodies (thyroid peroxidase antibodies)
Full details

Emerging tests

  • ultrasonography of thyroid
  • salivary CRP
Full details

Treatment algorithm

Contributors

Authors VIEW ALL

Associate Chief

Director of the Thyroid Health Center

Section of Endocrinology, Diabetes and Nutrition

Boston Medical Center

Associate Professor of Medicine

Boston University School of Medicine

Boston

MA

Disclosures

SLL declares that she has no competing interests.

Peer reviewers VIEW ALL

Professor of Medicine and Endocrinology

Medical Center Spijkenisse

The Hague

The Netherlands

Disclosures

Not disclosed.

Professor of Surgery

Virginia Commonwealth University

Richmond

VA

Disclosures

RM declares that he has no competing interests.

Consultant Endocrinologist

Epworth and Alfred Hospitals

Professor of Medicine

Monash University

Melbourne

Australia

Disclosures

At the time of review, JS declared that he had no competing interests. Unfortunately, we have since been made aware that JS is deceased.

Use of this content is subject to our disclaimer