Last reviewed: November 2017
Last updated: September  2016

Summary

Definition

History and exam

Key diagnostic factors

  • bilateral cleft lip ± palate
  • unilateral cleft lip ± palate
  • isolated cleft palate
  • microform cleft lip
  • isolated submucous cleft palate
  • positive prenatal ultrasound

Other diagnostic factors

  • difficulty feeding
  • poor weight gain
  • airway obstruction

Risk factors

  • genetic predisposition
  • dysmorphic syndrome
  • anticonvulsant drugs
  • maternal tobacco use
  • maternal alcohol consumption
  • folic acid deficiency

Diagnostic investigations

Investigations to consider

  • auditory brain stem response (ABR) test
  • vertebral spine x-rays
  • renal ultrasound
  • fluorescence in-situ hybridization (FISH)
Full details

Treatment algorithm

Contributors

Authors VIEW ALL

Travis T. Tollefson

Professor and Director

Facial Plastic and Reconstructive Surgery

Otolaryngology - Head and Neck Surgery

Cleft and Craniofacial Team

University of California Davis

Sacramento

CA

Disclosures

TTT is an author of studies referenced in this monograph.

David A. Shaye

Instructor

Facial Plastic and Reconstructive Surgery

Massachusetts Eye and Ear

Harvard University

Boston

MA

Disclosures

DAS declares that he has no competing interests.

Peer reviewers VIEW ALL

Assistant Professor to Director

Division of Facial Plastic and Reconstructive Surgery

Mayo Clinic

Rochester

MN

Disclosures

OF declares that he has no competing interests.

Professor of Pediatrics

Mayo Clinic

Rochester

MN

Disclosures

PF declares that he has no competing interests.

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