Deficiency of one or more pituitary hormones.
Variable presentation depending on cause.
Symptoms include headaches, amenorrhea, galactorrhea, and visual field defects.
Treatment depends on correction of the underlying cause. Where causes are not correctable, treatment focuses on replacing the target hormones.
Patients who require cortisol for ACTH deficiency require increased dosage in times of stress (such as infection, trauma, and surgery).
Hypopituitarism refers to the partial or complete deficiency of one or more pituitary hormones. It may arise as a congenital defect during the development of the pituitary gland or as a result of acquired diseases of the pituitary gland, the parasellar structures, or the hypothalamus.
Associate Professor of Medicine
Georgia Regents University
BS declares that she has no competing interests.
Dr Bridget Sinnott would like to gratefully acknowledge Dr Vidhi Shah, the previous contributor to this monograph. VS declares that she has no competing interests.
Associate Program Director
Department of Endocrinology, Diabetes and Metabolism
AH declares that he has no competing interests.
Newcastle Hospitals NHS Foundation Trust
Royal Victoria Infirmary
AJ declares that he has no competing interests.
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