Last reviewed: November 2017
Last updated: November  2017

Summary

Definition

History and exam

Key diagnostic factors

  • digoxin exposure
  • GI symptoms
  • CNS symptoms
  • visual symptoms

Other diagnostic factors

  • suicidality
  • cardiovascular symptoms

Risk factors

  • age >55 years
  • decreased renal clearance
  • hyperkalemia (>5.0 mEq/L)
  • hypokalemia (<3.0 to 3.5 mEq/L)
  • concomitant use of specific drugs
  • hypomagnesemia
  • hypercalcemia
  • hypothyroidism

Diagnostic investigations

1st investigations to order

  • ECG
  • digoxin serum concentration
  • serum potassium level
  • serum magnesium level
  • serum creatinine and BUN
Full details

Treatment algorithm

Contributors

Authors VIEW ALL

Associate Clinical Professor of Medicine

Department of Clinical Pharmacology and Toxicology

University of Colorado

Denver

CO

Disclosures

SP declares that he has no competing interests.

Dr Scott Phillips would like to gratefully acknowledge Dr Oladapo A. Odujube and Dr Robert S. Hoffman, previous contributors to this monograph. OAO and RSH declare that they have no competing interests.

Peer reviewers VIEW ALL

University of Massachusetts Medical School

Worcester

MA

Disclosures

EWB declares that he has no competing interests.

Consultant Physician and Clinical Toxicologist

National Poisons Information Service (Newcastle)

Newcastle-upon-Tyne

UK

Disclosures

RT declares that he has no competing interests.

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