The US Advisory Committee on Immunization Practices now recommends a 2-dose HPV immunization schedule for healthy adolescents ages 9 to 14 years. The second dose should be administered 6 to 12 months after the first dose.
For those who initiate the vaccination series at ages 15 to 26 years, and for immunocompromised persons, a 3-dose immunization schedule is still recommended.
Very common STD.
Caused by HPV infection, most commonly HPV types 6 and 11.
Peak incidence of genital HPV infection occurs in 16- to 25-year-olds.
Diagnosis is made based on clinical presentation.
Generally has a benign course and is not often associated with oncogenic potential.
Treatment can be challenging, as there is no cure and recurrences are common.
Genital warts are the most prevalent form of viral genital mucosal lesions and are caused by infection with several types of HPV.  The infection manifests as verrucous fleshy papules that may coalesce into plaques. Lesion size ranges from a few millimeters to several centimeters.  The warts may be located anywhere in the anogenital or genital area, including on mucosal surfaces.  The color can vary from whitish to flesh-colored to hyperpigmented to erythematous. Lesions typically appear within weeks to months after exposure to HPV.  They are generally asymptomatic, but may be painful, friable, or pruritic.   This monograph will cover diagnosis and treatment of internal and external warts, excluding cervical warts.
Department of Dermatology
University of Texas MD Anderson Cancer Center
NM declares that she has no competing interests.
Departments of Dermatology, Microbiology and Molecular Genetics and Internal Medicine
University of Texas Health Science Center
SKT declares that he has no competing interests.
Dr Natalia Mendoza and Dr Stephen K. Tyring would like to gratefully acknowledge Dr Brenda L. Pellicane, a previous contributor to this monograph. BLP declares that she has no competing interests.
Clinical Assistant Professor
University of Texas Medical Branch at Galveston
AM declares that she has no competing interests.
Consultant Genitourinary Physician
SB declares that he has no competing interests.
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