Last reviewed: November 2017
Last updated: September  2017

Summary

Definition

History and exam

Key diagnostic factors

  • erythema migrans
  • constitutional symptoms

Other diagnostic factors

  • facial palsy
  • arthritis or arthralgia
  • regional lymphadenopathy
  • stiff neck
  • lymphocytoma cutis
  • acrodermatitis chronica atrophicans
  • AV block or myopericarditis
  • radiculoneuropathy
  • encephalomyelitis, peripheral neuropathy, encephalopathy

Risk factors

  • exposure to infected ticks
  • outdoor activities
  • tick bite duration

Diagnostic investigations

Investigations to consider

  • Lyme-specific IgM and IgG
  • skin biopsy culture
  • PCR
  • ECG
Full details

Treatment algorithm

Contributors

Authors VIEW ALL

Janak Koirala

Professor of Medicine and Division Chief

Division of Infectious Diseases

Southern Illinois University School of Medicine

Springfield

IL

Disclosures

JK declares that he has no competing interests.

Janak Koirala would like to gratefully acknowledge Dr Tin Han Htwe and Dr Cristian A. Speil, previous contributors to this topic. TTH and CAS declare that they have no competing interests.

Peer reviewers VIEW ALL

Professor of Medicine and Microbiology/Immunology

Chief of Allergy, Immunology and Rheumatology

New York Medical College

Valhalla

NY

Disclosures

RJD declares that he has no competing interests.

Assistant Professor of Neurology and Neurosurgery

SUNY at Buffalo

Stroke/Neurocritical Care

Millard Fillmore Gates Hospital - Kaleida Stroke Center

Buffalo

NY

Disclosures

IC declares that she has no competing interests.

Lecturer in Tropical Medicine

University College Dublin

Medical Director

Tropical Medical Bureau

Ireland

Disclosures

GF declares that he has no competing interests.

Physician

Centre for Tick-Borne Diseases

Budapest

Hungary

Disclosures

AL is an author of a reference cited in this monograph.

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