Primarily a sexually transmitted disease caused by the fastidious, gram-negative coccobacillus Haemophilus ducreyi .
Common in Africa, Asia, and Latin America, but rare in developed countries.
Classically presents with the acute onset of a painful genital ulcer with fluctuant lymphadenitis (bubo formation).
An important co-factor in HIV transmission, and HIV status must be assessed.
Most cases resolve with antibiotic therapy; recurrence rare.
Sexual partners within 10 days prior to onset of symptoms must be traced and treated, even if asymptomatic.
Several reports now describe non-genital cutaneous limb ulcerations due to H ducreyi in yaws-endemic countries.
Chancroid is an infectious disease caused by the fastidious, gram-negative coccobacillus Haemophilus ducreyi , most commonly presenting with a genital ulcer, and often associated with fluctuant lymphadenitis.
Department of Medicine, Infectious Diseases
University of Rochester Medical Center
MAU declares that she has no competing interests.
Dr Marguerite A. Urban would like to gratefully acknowledge Dr Christina Bailey, a previous contributor to this monograph. CB declares that she has no competing interests.
GUM/HIV Camden Primary Care Trust
Archway Sexual Health Clinic
EJ declares that she has no competing interests.
Assistant Research Professor in Medicine
Indiana University Department of Medicine
School of Medicine
DMJ declares that she has no competing interests.
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