Last reviewed: November 2017
Last updated: November  2017

Summary

Differentials

Common

  • Trauma
  • Acute GI bleeding
  • Rupture of a vascular aneurysm
  • Surgery
  • Menorrhagia
  • Iron deficiency
  • Vitamin B12 deficiency
  • Folate deficiency
  • Myelodysplastic syndrome
  • Acute lymphocytic leukaemia
  • Acute myelogenous leukaemia
  • Chronic myelogenous leukaemia
  • Hairy cell leukaemia
  • Acquired aplastic anaemia
  • Infiltration by secondary malignancy
  • Pure red cell aplasia
  • Drug toxicity
  • Anaemia of chronic disease
  • Chronic kidney disease
  • Chronic liver disease
  • Pregnancy

Uncommon

  • Generalised malnutrition
  • Cytotoxic chemotherapy
  • Radiotherapy
  • Alcohol abuse
  • Lead toxicity
  • Hypothyroidism
  • Autoimmune haemolytic anaemia (AIHA)
  • Transfusion reaction
  • Malaria
  • Viral hepatitis
  • Toxoplasmosis
  • Leishmaniasis
  • Parvovirus B19 infection
  • Infectious mononucleosis
  • Cytomegalovirus (CMV)
  • Sickle cell anaemia
  • Thalassaemias
  • Hereditary spherocytosis
  • Glucose-6-phosphate dehydrogenase deficiency (G6PD)
  • Bone marrow failure syndromes
  • Haemolytic uraemic syndrome
  • Disseminated intravascular coagulation (DIC)
  • Thrombotic thrombocytopenic purpura
  • Haemangioma
  • Malignant hypertension
  • Prosthetic valves and surfaces
  • Cutaneous burns

Contributors

Authors VIEW ALL

Hematologist Oncologist

Baptist MD Anderson Cancer Center

Jacksonville

FL

Disclosures

RZ declares that he has no competing interests.

Dr Robert Zaiden would like to gratefully acknowledge Dr Fauzia Rana, a previous contributor to this monograph. FR declares that she has no competing interests.

Peer reviewers VIEW ALL

Associate Professor of Medicine

Innsbruck Medical University

Innsbruck

Austria

Disclosures

CP declares that he has no competing interests.

Associate Professor of Clinical Medicine

Department of Medicine

Division of Hematology/Oncology

University of Virginia

Charlottesville

VA

Disclosures

JD declares that he has no competing interests.

Internal Medicine Instructor

Member of Evidence Based Medicine Unit

Catholic University of Chile

Santiago

Chile

Disclosures

CA declares that he has no competing interests.

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