Last reviewed: November 2017
Last updated: October  2017

Summary

Definition

History and exam

Key diagnostic factors

  • presence of risk factors
  • malpositioned or absent testis
  • palpable cryptorchid testis
  • non-palpable testis

Other diagnostic factors

  • testicular asymmetry
  • scrotal hypoplasia or asymmetry
  • retractile testis
  • ascending cryptorchidism
  • hypospadias
  • micropenis
  • secondary sex characteristics/pubertal signs in prepubertal/pubertal patients
  • surgical scar in the inguinal region

Risk factors

  • FHx cryptorchidism
  • prematurity
  • low birth weight (<2.5 kg) and/or small for gestational age
  • environmental exposures
  • maternal alcohol use
  • gestational diabetes
  • prior inguinal surgery

Diagnostic investigations

Investigations to consider

  • ultrasound
  • MRI
  • hormonal evaluation with human chorionic gonadotrophin (hCG) stimulation test
  • hormonal evaluation with Mullerian inhibiting substance (MIS), inhibin B, and FSH
  • karyotyping
Full details

Treatment algorithm

Contributors

Authors VIEW ALL

David J. Chalmers

Pediatric Urology

Maine Medical Center

Portland

ME

Disclosures

DJC declares that he has no competing interests.

Dr David J. Chalmers would like to gratefully acknowledge Dr Gabriel Belanger, Dr Duncan T. Wilcox, and Dr Nicol Corbin Bush, previous contributors to this topic. DTW and NCB declare that they have no competing interests.

Peer reviewers VIEW ALL

Professor Pediatric Urology

Hospital for Sick Children

Toronto

Canada

Disclosures

MK declares that he has no competing interests.

Professor of Urology

Endowed Chair

Urologic Education

The University of California

San Francisco

CA

Disclosures

PJT declares that he has no competing interests.

Lecturer in Uro-oncology and Consultant Urological Surgeon

Department of Urology

Addenbrooke's Hospital

Cambridge

UK

Disclosures

VG declares that he has no competing interests.

Professor and Head

Department of Pediatric Surgery

Rigshospitalet, University of Copenhagen

Copenhagen

Denmark

Disclosures

JT is an author of a reference cited in this monograph.

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