Last reviewed: November 2017
Last updated: December  2017

Summary

Definition

History and exam

Key diagnostic factors

  • presence of risk factors
  • acral and periorificial depigmentation
  • perianal and genital depigmentation
  • universal depigmentation
  • recent cutaneous trauma
  • localised sunburn pain
  • enhancement and fluorescence with UV-A exposure
  • halo naevus
  • lip depigmentation
  • erythema, oedema, or blistering
  • retinal depigmentation

Risk factors

  • age <30 years
  • FHx of vitiligo
  • auto-immune disease
  • chemical contact

Diagnostic investigations

Treatment algorithm

Contributors

Authors VIEW ALL

Associate Professor

Department of Dermatology

University of Massachusetts Medical School

Worcester

MA

Disclosures

JEH has received consulting fees and/or research grants from the following: Pfizer, AbbVie, Genzyme/Sanofi, Concert Pharmaceuticals, Stiefel/GSK, Mitsubishi Tanabe Pharma, Novartis, Aclaris Therapeutics, The Expert Institute, Celgene, Biologics MD, and Dermira. JEH is an author of a number of references cited in this monograph.

Physician Resident

Department of Dermatology

University of Massachusetts Medical School

Worcester

MA

Disclosures

MR is an author of a number of references cited in this monograph.

Dr John E. Harris and Dr Mehdi Rashighi would like to gratefully acknowledge Dr Bernhard Ortel, a previous contributor to this monograph. BO declares that he has no competing interests.

Peer reviewers VIEW ALL

Senior Staff Physician

Multicultural Dermatology Center

Henry Ford Hospital

Detroit

MI

Disclosures

IH is an author of a number of references cited in this monograph.

Chair

Dermatology Department

University of Brescia

Brescia

Italy

Disclosures

PC-P is an author of a number of references cited in this monograph.

Use of this content is subject to our disclaimer