Last reviewed: November 2017
Last updated: March  2017

Summary

Definition

History and exam

Key diagnostic factors

  • presence of risk factors
  • diarrhoea

Other diagnostic factors

  • generalised abdominal pain
  • RU abdominal pain
  • weight loss
  • cough
  • fever
  • altered mental status or limb weakness
  • dyspnoea
  • guarding and rebound tenderness of the abdomen
  • jaundice
  • right lung decreased air entry and percussion note

Risk factors

  • exposure in endemic areas
  • institutionalisation of mentally retarded people
  • men who have sex with men
  • male sex

Diagnostic investigations

1st investigations to order

  • stool antigen detection
  • PCR or qPCR of stool or liver abscess pus for E histolytica DNA
  • serum antibody test
Full details

Investigations to consider

  • stool microscopy
  • colonoscopy
  • liver ultrasound
  • CXR
  • CT liver/chest/head
  • MRI brain
Full details

Treatment algorithm

Contributors

Authors VIEW ALL

William A. Petri, Jr

Wade Hampton Frost Professor of Epidemiology

Professor of Medicine, Microbiology, and Pathology

Chief

Division of Infectious Diseases and International Health

University of Virginia

Charlottesville

VA

Disclosures

WAP receives income from the University of Virginia for licensing fees for amebiasis diagnostics produced by TechLab, Inc. These are donated in their entirety to the American Society of Tropical Medicine and Hygiene by Dr Petri. WAP is also the author of a number of references cited in this monograph.

Visiting Professor

Department of Infectious Diseases and International Health

University of Virginia

Charlottesville

VA

Disclosures

KW declares that he has no competing interests.

Peer reviewers VIEW ALL

Senior Lecturer in Microbiology and Medicine

Department of Clinical Microbiology and Infectious Diseases

Hadassah-Hebrew University Medical Center

Jerusalem

Israel

Disclosures

RNP declares that he has no competing interests.

Assistant Professor of Medicine

Division of Infectious Diseases

University of Vermont College of Medicine

Burlington

VT

Disclosures

CH declares that he has no competing interests.

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