Last reviewed: October 2017
Last updated: November  2017

Summary

Definition

History and exam

Key diagnostic factors

  • presence of risk factors
  • abdominal pain
  • weight loss
  • lymphadenopathy

Other diagnostic factors

  • age 50 to 70 years
  • male sex
  • smoking
  • positive FHx
  • nausea
  • dysphagia
  • lower GI bleeding

Risk factors

  • pernicious anaemia
  • Helicobacter pylori
  • N-nitroso compounds
  • diet low in fruits and vegetables
  • high-salt diet
  • smoking
  • positive FHx

Diagnostic investigations

1st investigations to order

  • upper GI endoscopy with biopsy
Full details

Investigations to consider

  • endoscopic ultrasound (EUS)
  • CT abdomen/pelvis
  • CXR
  • CT chest
  • laparoscopy
  • PET/CT scan
Full details

Treatment algorithm

Contributors

Authors VIEW ALL

Assistant Professor

Department of GI Medical Oncology

University of Texas

MD Anderson Cancer Center

Houston

TX

Disclosures

MBM declares that she has no competing interests.

Assistant Professor

Department of Radiation Oncology

University of Texas

MD Anderson Cancer Center

Houston

TX

Disclosures

VR declares that she has no competing interests.

Peer reviewers VIEW ALL

Director

Gastrointestinal Radiation Oncology

Massachusetts General Hospital Cancer Center

Boston

MA

Disclosures

TH declares that he has no competing interests.

Head of Department

Department of Gastroenterology

Sana Klinikum

Remscheid

Germany

Disclosures

AL declares that he has no competing interests.

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