Most commonly presents as a hard, painless nodule on one testis noticed by the patient or at a regular clinic examination.
Elevated serum tumour markers are diagnostic of the disease and aid in monitoring the treatment response.
Ultrasound of the testis is 90% to 95% accurate in diagnosis.
Radical orchiectomy to confirm histological diagnosis is initial treatment in most cases.
Infertility is a complication of surgery.
The most common malignancy in young adult men (20 to 34 years of age), and highly curable when diagnosed early. A precancerous condition termed carcinoma in situ is highly specific early in the natural history of the disease.
Associate Professor of Surgery/Urology
Director of Prostate Cancer Fellowship Program
School of Medicine
University of Colorado Denver
ABB declares that he has no competing interests.
University of Colorado Denver School of Medicine
University of Colorado Cancer Center
ERK declares that she has no competing interests.
Dr Al B. Barqawi and Dr Elizabeth R. Kessler would like to gratefully acknowledge Dr Thomas W. Flaig, a previous contributor to this monograph. TWF declares that he has no competing interests.
Assistant Professor of Medicine and Oncology
Karmanos Cancer Institute
Wayne State University
EH declares that she has no competing interests.
Consultant/Honorary Senior Lecturer in Medical Oncology
SW Wales Cancer Institute/Department of Oncology
GB declares that he has no competing interests.
Senior Lecturer in Medical Oncology
School of Cancer Sciences
University of Birmingham
EP declares that he has no competing interests.
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