Last reviewed: November 2017
Last updated: October  2017

Summary

Definition

History and exam

Key diagnostic factors

  • presence of risk factors
  • dysphagia
  • food avoidance and modification behaviours

Other diagnostic factors

  • heartburn
  • chest discomfort
  • nausea/vomiting
  • regurgitation
  • abdominal pain
  • failure to thrive
  • irritability

Risk factors

  • family history of eosinophilic oesophagitis (EoO)
  • male sex
  • atopic disease
  • children and younger adults
  • white ancestry

Diagnostic investigations

1st investigations to order

  • oesophagogastroduodenoscopy (OGD)
  • oesophageal biopsy
  • proton-pump inhibitor (PPI) trial
  • FBC with differential
Full details

Emerging tests

  • transnasal endoscopy
  • oesophageal string test
  • cytosponge
  • mucosal impedance
  • EoO diagnostic panel
Full details

Treatment algorithm

Contributors

Authors VIEW ALL

Associate Professor of Medicine and Epidemiology

Center for Esophageal Diseases and Swallowing

Center for Gastrointestinal Biology and Disease

Division of Gastroenterology and Hepatology

Department of Medicine

University of North Carolina School of Medicine

Chapel Hill

NC

Disclosures

ESD is an author of a number of references cited in this monograph.

Peer reviewers VIEW ALL

Professor of Medicine

Mayo Clinic

Rochester

MN

Disclosures

DK has served on advisory boards (Adare, Receptos) and received research funding (Covidien).

Honorary Professor

Chief of the Division of Gastroenterology and Hepatology

First Department of Pediatrics

University of Athens

Agia Sofia Children’s Hospital

Athens

Greece

Disclosures

AP has received speaker’s honorariums from Nestle and Nutricia; research grants from Biogaia/Nutricia/Abbvie; consultant’s fee from Receptos.

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