Last reviewed: November 2017
Last updated: November  2017

Summary

Definition

History and exam

Key diagnostic factors

  • presence of risk factors
  • cervical or generalised lymphadenopathy
  • pharyngitis
  • malaise
  • fever

Other diagnostic factors

  • splenomegaly
  • hepatomegaly
  • rash
  • jaundice
  • myalgia

Risk factors

  • kissing
  • sexual behaviour

Diagnostic investigations

1st investigations to order

  • FBC
  • heterophile antibodies
  • EBV-specific antibodies
  • real-time PCR
Full details

Investigations to consider

  • CT of abdomen
  • ultrasonography of abdomen
Full details

Treatment algorithm

ACUTE

Contributors

Authors VIEW ALL

Medical Epidemiologist

Missouri Department of Health and Senior Services

Adjunct Assistant Professor of Clinical Pediatrics

Washington University School of Medicine

Adjunct Associate Professor of Pediatrics

Child Health Department

University of Missouri

St Louis

MO

Disclosures

GT declares that he has no competing interests.

Peer reviewers VIEW ALL

Epidemiologist

College of Medicine

University of Malawi

Zomba

Malawi

Disclosures

LK declares that she has no competing interests.

Clinical Director

Division of Infectious Diseases

Associate Professor of Medicine

Divisions of Infectious Diseases and General Internal Medicine

Johns Hopkins University School of Medicine

Baltimore

MD

Disclosures

PGA declares that he has no competing interests.

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