Last reviewed: November 2017
Last updated: November  2017

Summary

Definition

History and exam

Key diagnostic factors

  • presence of risk factors
  • abdominal discomfort
  • alteration of bowel habits associated with pain
  • abdominal bloating or distension
  • normal examination of abdomen

Other diagnostic factors

  • passage of mucus with stool

Risk factors

  • physical and sexual abuse
  • age <50 years
  • female gender
  • previous enteric infection
  • family and job stress

Diagnostic investigations

1st investigations to order

  • FBC
  • stool studies
  • anti-endomysial antibodies
  • anti-tTG antibodies
  • plain abdominal x-ray
  • flexible sigmoidoscopy
  • colonoscopy
Full details

Investigations to consider

  • hydrogen breath test
  • faecal calprotectin
  • serum CRP
Full details

Treatment algorithm

Contributors

Authors VIEW ALL

Chief of Gastroenterology and Hepatology

Kelsey-Seybold Clinic

Clinical Professor of Medicine

Baylor College of Medicine

Houston

Adjunct Professor of Medicine

University of Texas Medical Branch

Galveston

TX

Disclosures

NS declares that he has no competing interests.

Peer reviewers VIEW ALL

Professor of Medicine and Psychiatry

School of Medicine

Co-Director

UNC Center for Functional GI and Motility Disorders

Chapel Hill

NC

Disclosures

DD declares that he has no competing interests.

Research Fellow

Department of Gastroenterology

St Mark's Hospital

Northwick Park

Harrow

UK

Disclosures

SM declares that he has no competing interests.

Clinical Research Fellow

Division of Medicine

Imperial College

London

UK

Disclosures

HW declares that he has no competing interests.

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