Last reviewed: October 2017
Last updated: November  2017

Summary

Differentials

Common

  • Septic non-gonococcal arthritis
  • Gonococcal arthritis
  • Rheumatoid arthritis
  • Gout
  • Pseudogout

Uncommon

  • Indolent infections
  • Parvoviral syndrome
  • Lyme disease
  • Juvenile idiopathic arthritis (oligo-articular type)
  • Acute rheumatic fever (ARF)
  • Sarcoidosis
  • Spondyloarthropathy
  • Systemic lupus erythematosus (SLE)
  • Adult-onset Still's disease (AOSD)
  • Psoriatic arthritis
  • Reactive arthritis
  • Ankylosing spondylitis (AS)
  • Osteoarthritis
  • Trauma
  • Non-traumatic haemarthrosis
  • Hypertrophic osteoarthropathy
  • Intra-articular metastatic cancer
  • Synovial sarcoma
  • Arbovirus infections (e.g., chikungunya)
  • SAPHO syndrome
  • Drug-induced
  • Remitting seronegative symmetrical synovitis with pitting oedema (RS3PE) syndrome
  • Ebola virus
  • Diffuse pigmented villonodular synovitis
  • Localised pigmented villonodular synovitis
  • Synovial osteochondromatosis
  • Amyloid arthropathy
  • Fibroblastic rheumatism

Contributors

Authors VIEW ALL

Associate Professor of Medicine

Cleveland Clinic Lerner College of Medicine of Case Western Reserve University

Staff Physician

Department of Rheumatologic and Immunologic Disease

Orthopedic and Rheumatologic Institute

Cleveland Clinic

Cleveland

OH

Disclosures

SC declares that he has no competing interests.

Peer reviewers VIEW ALL

Professor of Rheumatology

University of Cambridge

Clinical Director

West Anglia CLRN

Cambridge

UK

Disclosures

HG declares that he has no competing interests.

Chief of Rheumatology

Director

Arthritis-Fibromyalgia Center

Newton-Wellesley Hospital

Newton

Professor of Medicine

Tufts University School of Medicine

Boston

MA

Disclosures

DLG declares that he has no competing interests.

Associate Professor

Division of Orthopedic Surgery

University of Alabama

Birmingham

AL

Disclosures

BAP declares that he has no competing interests.

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