Last reviewed: November 2017
Last updated: December  2016

Summary

Definition

History and exam

Key diagnostic factors

  • presence of risk factors
  • erythema or ulceration of oral mucosa
  • oral pain

Other diagnostic factors

  • dietary impairment
  • diarrhoea
  • xerostomia
  • fever

Risk factors

  • intensive chemotherapy regimens
  • radiotherapy to the oral cavity
  • chemoradiation
  • genetic polymorphisms in drug metabolic enzymes

Diagnostic investigations

Investigations to consider

  • FBC and differential
  • blood cultures
  • superficial smear of lesion for microscopy
  • fungal culture
  • viral culture or PCR
Full details

Treatment algorithm

Contributors

Authors VIEW ALL

Associate Professor

Associate Dean for Research

Section of Oral Medicine

University of Connecticut School of Dental Medicine

Farmington

CT

Disclosures

RVL serves as a consultant for Galera Therapeutics, Ingalfarma, and Sucampo Pharma, and has received research funding from Onxeo, Sucampo Pharma, and Novartis.

Peer reviewers VIEW ALL

Associate Chairman and Oral Medicine Residency Director

Department of Oral Medicine

Carolinas Medical Center

Charlotte

NC

Disclosures

MB is an author of a reference cited in this monograph. MB is part of the Mucositis Study Group of MASCC/ISOO, and participated in the review of mucositis.

Consultant Pediatric and Adolescent Oncologist

University College London Hospitals

London

UK

Disclosures

MM declares that she has no competing interests.

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