Last reviewed: November 2017
Last updated: May  2017

Summary

Definition

History and exam

Key diagnostic factors

  • presence of risk factors
  • sudden-onset focal neurological deficit
  • seizures
  • reduced conscious level

Other diagnostic factors

  • sudden-onset headache
  • nausea
  • vomiting
  • confusion
  • gradual-onset headaches
  • hypertension
  • coma
  • gradual-onset focal neurological deficit
  • cognitive dysfunction

Risk factors

  • familial (malformation)
  • previous haemorrhages (risk of haemorrhage)
  • drug abuse (risk of haemorrhage)
  • abnormal venous drainage (risk of haemorrhage)
  • small AVMs (risk of haemorrhage)
  • posterior fossa and deep AVMs (risk of haemorrhage)
  • co-existing aneurysms (risk of haemorrhage)
  • seizures (risk of haemorrhage)
  • pregnancy (risk of haemorrhage)
  • hypertension (risk of haemorrhage)

Diagnostic investigations

Investigations to consider

  • brain digital subtraction angiogram
  • brain CT angiogram
  • brain MR angiogram
  • FBC
  • clotting screen and group
  • electrolyte panel
  • drug toxicology screen
  • functional imaging
  • superselective Wada
  • neuropsychology
  • perfusion studies
  • EEG
  • visual fields
Full details

Emerging tests

  • 4D CT angiography (CTA)/MR angiography (MRA)
Full details

Treatment algorithm

Contributors

Authors VIEW ALL

Director of Medical Studies (Neurosurgey)

Assistant Professor

Section of Neurovascular Surgery

Departments of Neurosurgery & Diagnostic Radiology

Yale University, School of Medicine

Yale University HHT Center

Brain Aneurysm & AVM Program and Stroke Program

Yale-New Haven Hospital

New Haven

CT

Disclosures

CM declares that he has no competing interests.

Dr Charles Matouk would like to gratefully acknowledge Dr Catherine E. Gilkes and Dr Richard J. Edwards, the previous contributors to this monograph, and the additional contribution of Dr Branden Cord and Dr Ryan Hebert. CEG and RJE declare that they have no competing interests.

Peer reviewers VIEW ALL

Chairman

Professor of Neurosurgery

Department of Neurosurgery

Technical University of Munich

Munich

Germany

Disclosures

BM declares that he has no competing interests.

Assistant Professor of Neurology

Neurosurgery and Radiology

Rush University Medical Center

Chicago

IL

Disclosures

MC declares that he has no competing interests.

Research Director

Stroke Center/The Neurological Institute

Columbia-Presbyterian Medical Center

New York

NY

Disclosures

JHC declares that he has no competing interests.

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