Last reviewed: November 2017
Last updated: November  2017

Summary

Definition

History and exam

Key diagnostic factors

  • presence of risk factors
  • upper or lower limb claudication
  • absent pulse(s)
  • unequal blood pressures
  • vascular bruits
  • low-grade fever

Other diagnostic factors

  • transient ischaemic attack (TIA)
  • myalgia
  • arthralgia
  • weight loss
  • fatigue
  • dizziness on upper-limb exertion
  • hypertension
  • stroke
  • chest pain
  • abdominal pain
  • diarrhoea
  • shortness of breath
  • haemoptysis
  • night sweats
  • vertigo
  • syncope
  • headache
  • heart murmur
  • visual symptoms
  • erythema nodosum
  • pyoderma gangrenosum

Risk factors

  • genetic predisposition
  • female sex
  • age <40
  • Asian ethnicity

Diagnostic investigations

1st investigations to order

  • ESR
  • CRP
  • computerised tomography angiography (CTA)
  • magnetic resonance imaging angiography (MRA)
Full details

Investigations to consider

  • catheter angiogram
  • Doppler ultrasound
  • positron emission tomography with radiolabelled fluorodeoxyglucose (PET-FDG)
Full details

Treatment algorithm

ACUTE

Contributors

Authors VIEW ALL

Steven R. Ytterberg

Associate Professor of Medicine

Mayo Clinic College of Medicine

Rochester

MN

Disclosures

SRY declares that he was a sub-awardee of a grant from the US Food and Drug Administration for a pilot study of abatacept, a treatment for Takayasu's arteritis. SY is also a member of the steering committee at the Vasculitis Clinical Research Committee.

Kenneth J. Warrington

Professor of Medicine

Mayo Clinic College of Medicine

Rochester

MN

Disclosures

KJW declares that he has no competing interests.

Eric L. Matteson

Professor of Medicine

Mayo Clinic College of Medicine

Rochester

MN

Disclosures

ELM declares that he has no competing interests.

Peer reviewers VIEW ALL

Internal Medicine

Hopital Cochin-Paris University

St-Jacques

Paris

France

Disclosures

LPG declares that he has no competing interests.

Department of Medicine

Division of Rheumatology

Mayo Clinic

Rochester

MN

Disclosures

GGH is an author of a reference cited in this monograph. GGH declares that he has no other competing interests.

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