Last reviewed: November 2017
Last updated: November  2017

Summary

Differentials

Common

  • Infection
  • Inflammatory conditions
  • Chronic myeloid leukaemia (CML)
  • Essential thrombocytosis
  • Polycythaemia vera
  • Primary myelofibrosis

Uncommon

  • Platelet clumping
  • Cryoglobulinaemia
  • Anaemia
  • Solid tumour malignancy
  • Bone marrow infiltration
  • Heat stroke
  • Chronic bone marrow stimulation
  • Asplenia
  • Sweet's syndrome
  • Drug-induced haematopoiesis
  • Chronic neutrophilic leukaemia
  • Myelodysplastic syndrome
  • Acute myeloid leukaemia
  • Hereditary neutrophilia
  • Pelger-Huet abnormality
  • Amegakaryocytic thrombocytopenia
  • Trisomy 21 (Down's syndrome)
  • Leukocyte adhesion deficiency type I
  • Familial cold autoinflammatory syndrome
  • Chronic idiopathic neutrophilia
  • Stress-induced demargination
  • Drug-induced demargination
  • Drug-induced decreased egress

Contributors

Authors VIEW ALL

Assistant Professor of Pathology

University of New Mexico Health Sciences Center

Albuquerque

NM

Disclosures

DCR declares that she has no competing interests.

Professor of Pathology

University of New Mexico Health Sciences Center

Albuquerque

NM

Disclosures

TIG declares that she has received consulting fees from Wiley Blackwell as coeditor-in-chief for the International Journal of Laboratory Hematology, royalties from Wolters Kluwer for an atlas on peripheral blood smears, and royalties from UpToDate, Inc. for an online chapter on automated hematology.

Dr Devon Chabot-Richards and Dr Tracy I. George would like to gratefully acknowledge Dr Holbrook Kohrt, a previous contributor to this monograph. HK declares that he has no competing interests.

Peer reviewers VIEW ALL

Professor

Department of Pathology

University of New Mexico Health Sciences Center

Albuquerque

NM

Disclosures

CW declares that she has no competing interests.

Professor of Pathology

Medical Director of Hematopathology

University of Utah Health Sciences and ARUP Laboratories

Salt Lake City

UT

Disclosures

SP declares that she has no competing interests.

Consultant Haematologist

Royal Hallamshire Hospital

Professor

University of Sheffield

Sheffield

UK

Disclosures

JR declares that he has no competing interests.

Consultant Haematologist

University Hospital Bristol

Bristol

UK

Disclosures

PM declares that she has no competing interests.

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