- The most common form of nephrotic syndrome in children, characterised by minimal histological changes in the kidney; 90% of cases are idiopathic.
- Children typically present with peripheral oedema, although some are asymptomatic. Diagnosis is usually made on clinical grounds.
- Corticosteroid therapy is mainstay of treatment. Long-term corticosteroid therapy has significant adverse effects; therefore, if needed, corticosteroid-sparing therapies can be added.
- Renal biopsy usually reserved for those patients who do not respond to corticosteroid therapy or have frequent relapses, or for diagnosis of patients <1 year old.
Other related conditions
- Assessment of nephrotic syndrome
- Assessment of proteinuria
- Assessment of peripheral oedema
- Chronic congestive heart failure
- IgA nephropathy
- Membranous nephropathy
- Spontaneous bacterial peritonitis
- Hypercoagulable state
- Assessment of hypertension
Last updated: Nov 09, 2012