Resumen
- Hereditary tumour syndromes with distinct patterns of organ involvement.
- Mutations in the MEN1 gene typically cause type 1 multiple endocrine neoplasia (MEN1), and mutations in the RET proto-oncogene typically cause type 2 multiple endocrine neoplasia (MEN2).
- Prophylactic thyroidectomy in childhood is indicated in MEN2.
- Medical management of hormonal hypersecretion is important for symptom control.
- Most tumours require surgical evaluation, although surgical cure is not always possible.
- Genetic carriers require lifelong monitoring, even after successful operations.
- Morbidity and mortality result from both hormonal hypersecretion and metastases.
Otras enfermedades relacionadas
- Primary hyperparathyroidism
- Oropharyngeal cancer
- Primary hyperparathyroidism
- Pancreatic cancer
- Colorectal cancer
- Stomach cancer
- Oesophageal cancer
- Thyroid cancer
- Thyroid cancer
- Primary hyperparathyroidism
- Secondary hyperparathyroidism
- Phaeochromocytoma
- Pituitary adenoma
- Zollinger-Ellison syndrome
- Atrial myxoma
- Hirschsprung's disease
- Amyloidosis
Actualizado por última vez: abr 03, 2013
