- Usually presents as chronic, upper abdominal pain related to eating a meal (dyspepsia).
- Use of nonsteroidal anti-inflammatory drugs (NSAIDs) and Helicobacter pylori infection are the most common causes.
- There may be some epigastric tenderness, but often there are no other signs on physical examination.
- Endoscopy is diagnostic and may show an ulcer in the stomach or proximal duodenum. H pylori infection should be sought.
- In the absence of "alarm" (red flag) symptoms or signs, testing for and treating H pylori and/or empirical acid inhibition therapy is appropriate.
- Most common complications are gastroduodenal bleeding and perforation, either of which may be the presenting symptom, particularly in patients taking NSAIDs.
Other related conditions
- Assessment of pleuritis
- Assessment of upper gastrointestinal bleeding
- Coeliac disease
- Crohn's disease
- Gastro-oesophageal reflux disease
- Irritable bowel syndrome
- Oesophageal cancer
- Overview of HIV
- Acute pancreatitis
- Pyloric stenosis
- Smoking cessation
- Stomach cancer
- Zollinger-Ellison syndrome
Last updated: Apr 25, 2012