- Non-alcoholic hepatic steatosis, or non-alcoholic fatty liver disease, is the most common cause of chronic liver disease in the Western world.
- It is projected to become a leading indication for liver transplantation, superseding hepatitis C.
- The diagnosis of hepatic steatosis is based on exclusion of other aetiologies, such as alcohol use, along with histology.
- Associated with obesity and features of the metabolic syndrome in most cases. May progress to steatohepatitis and end-stage liver disease.
- There are no currently recommended drug treatments. Lifestyle modification remains the first-line therapy.
Last updated: Oct 05, 2012