Addison's disease

Summary

  • Presentation may be acute or insidious, with substantial fatigue and weakness associated with mucocutaneous hyperpigmentation, hypotension and/or postural hypotension, and salt craving.
  • ACTH stimulation test is performed to confirm or exclude the diagnosis of Addison's disease.
  • All patients receive mineralocorticoid and glucocorticoid replacement for life, and are instructed to increase the dose of glucocorticoid during surgery and during any stressful or infectious conditions.
  • Treatment complications arise from over-replacement of mineralocorticoid and/or glucocorticoid.
Last updated: Apr 09, 2013
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