- Typically presents as a progressive, life-threatening, chronic or subacute meningitis.
- Occurs most commonly in immunosuppressed individuals and is often accompanied by systemic involvement.
- Cerebrospinal fluid typically shows lymphocytic pleocytosis, elevated protein, and low glucose.
- The commonest type of fungal meningitis is cryptococcal meningitis.
- A rapid aetiological diagnosis is required to guide antifungal therapy.
- Complications include seizures, cerebral infarction, hydrocephalus, and elevated CSF pressure without hydrocephalus.
Last updated: Oct 29, 2012